chemical

Guggulsterone

2013

10 mg (also 50 mg)

175 USD

2013

2013/10

Guggulsterone

Broad spectrum steroid receptor ligand. Antagonizes FXR and displays hypolipidemic activity

Additional Nuclear Receptor Compounds

Small Molecules

10 mg (also 50 mg)

99%

312.45

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Broad spectrum steroid receptor ligand; binds with high affinity to mineralocorticoid receptors (Ki = 39 nM) and lower affinity to progesterone, androgen and glucocorticoid receptors (Ki values are 201, 240 and 224 nM respectively). Functions primarily as an antagonist of these receptors, with the exception of the progesterone receptor where it displays partial agonist effects. Also exerts hypolipidemic activity, likely via antagonism of the receptor for bile acids (farnesoid X receptor; FXR). . This compound is a mixture of ( Z )- and ( E )-Guggulsterone in a ratio of approximately 60:40.

2013

Broad spectrum steroid receptors ligands Antagonizes antagonists FXR hypolipidaemic Other Nuclear Receptors 2013,

Broad spectrum steroid receptor ligand. Antagonizes FXR and displays hypolipidemic activity

Pregna-4,17(20)-diene-3,16-dione

C 21 H 28 O 2

C21H28O2

95975-55-6

175

175 USD

Store at RT