Guggulsterone | Tocris Bioscience 2013/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Guggulsterone

catalog :

2013/10

quantity :

10 mg

price :

193 USD

product information

brand :

Tocris

master code :

2013

SKU :

2013/10

product name :

Guggulsterone

unit size :

10 mg

description :

The Recombinant Human KIR2DL3/CD158b2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human KIR2DL3/CD158b2 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Additional Nuclear Receptor Compounds

category :

Small Molecules

purity :

99%

storage :

Store at RT

observed molecular weight :

312.45

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Guggulsterone is a broad spectrum steroid receptor ligand; binds with high affinity to mineralocorticoid receptors (Ki = 39 nM) and lower affinity to progesterone, androgen and glucocorticoid receptors (Ki values are 201, 240 and 224 nM respectively). Functions primarily as an antagonist of these receptors, with the exception of the progesterone receptor where it displays partial agonist effects. Also exerts hypolipidemic activity, likely via antagonism of the receptor for bile acids (farnesoid X receptor; FXR). . This compound is a mixture of ( Z )- and ( E )-Guggulsterone in a ratio of approximately 60:40.

extended description :

Broad spectrum steroid receptor ligand. Antagonizes FXR and displays hypolipidemic activity

chemical name text :

Pregna-4,17(20)-diene-3,16-dione

formula :

C 21 H 28 O 2

formula text :

C21H28O2

cas num :

95975-55-6

USD :

182

Jul-22 :

193 USD

product details :

Broad spectrum steroid receptor ligand. Antagonizes FXR and displays hypolipidemic activity

sizes available :

10 mg (also 50 mg)