PSB 11 hydrochloride | Tocris Bioscience 2012 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PSB 11 hydrochloride

catalog :

2012

quantity :

10 mg (also 50 mg)

price :

189 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

2012

SKU :

2012/10

product name :

PSB 11 hydrochloride

description :

Potent, selective hA3 receptor antagonist/inverse agonist

target :

Adenosine A3 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

331.8

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective antagonist for the human adenosine A3 receptor, with low affinity for the rat A3 receptor (Ki values are 2.3 and 10000 nM respectively). Displays 1000-fold selectivity over human A1 and A2A receptors (Ki values are 4.1 and 3.3 u M respectively) and 180-fold selectivity over rat A1, rat A2A and mouse A2B receptors. Acts as an inverse agonist in the [35S]GTP S binding assay in hA3-CHO cells (IC50 = 36 nM).

catalog number base :

2012

product keywords :

Potent selective human A3 receptor antagonists inverse agonists Receptors adenosines PSB11 hydrochloride Adenosine A3 Receptors 2012,

extended description :

Potent, selective hA3 receptor antagonist/inverse agonist

chemical name text :

(8R)-8-Ethyl-1,4,7,8-tetrahydro-4-5H-imidazo[2,1-i]purin-5-one hydrochloride

formula :

C 16 H 17 N 5 O.HCl

formula text :

C16H17N5O.HCl

cas num :

453591-58-7

2020 USD :

210

2021 USD :

189 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage