product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
Tomoxetine hydrochloride
catalog :
2011
quantity :
10 mg (also 50 mg)
price :
195 USD
more info or order :
citations: 5
Reference
Achterberg E, van Kerkhof L, Damsteegt R, Trezza V, Vanderschuren L. Methylphenidate and atomoxetine inhibit social play behavior through prefrontal and subcortical limbic mechanisms in rats. J Neurosci. 2015;35:161-9 pubmed publisher
Finnema S, Hughes Z, Haaparanta Solin M, Stepanov V, Nakao R, Varnäs K, et al. Amphetamine decreases α2C-adrenoceptor binding of [11C]ORM-13070: a PET study in the primate brain. Int J Neuropsychopharmacol. 2014;18: pubmed publisher
Conley J, Meyer J, Nuss A, Doyle T, Savinov S, Hill C, et al. Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti. J Pharmacol Exp Ther. 2015;352:53-60 pubmed publisher
Parker M, Brock A, Sudwarts A, Brennan C. Atomoxetine reduces anticipatory responding in a 5-choice serial reaction time task for adult zebrafish. Psychopharmacology (Berl). 2014;231:2671-9 pubmed publisher
Kobayashi T, Washiyama K, Ikeda K. Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine. Neuropsychopharmacology. 2010;35:1560-9 pubmed publisher
product information
brand :
Tocris
master code :
2011
SKU :
2011/10
product name :
Tomoxetine hydrochloride
description :
Potent and selective noradrenalin re-uptake inhibitor
target :
Adrenergic Transporter Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
291.82
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). Displays minimal affinity for a range of other neurotransmitter receptors and transporters (Ki 1 u M). Antidepressant.
catalog number base :
2011
product keywords :
Potent selective noradrenaline noradrenalin reuptake inhibitors inhibits Transporters adrenaline adrenalin NET Adrenergic Monoamine Neurotransmitter LY139603 Atomoxetine LY 139603 Adrenergic Transporters 2011,
extended description :
Potent and selective noradrenalin re-uptake inhibitor
chemical name text :
(R)-N-Methyl- -(2-methylphenoxy)-benzenepropanamine hydrochloride
formula :
C 17 H 21 NO.HCl
formula text :
C17H21NO.HCl
cas num :
82248-59-7
2020 USD :
187
2021 USD :
195 USD
alt names :
Atomoxetine, LY 139603
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK