Tomoxetine hydrochloride | Tocris Bioscience 2011/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Tomoxetine hydrochloride

catalog :

2011/10

quantity :

10 mg (also 50 mg)

price :

251 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Achterberg E, van Kerkhof L, Damsteegt R, Trezza V, Vanderschuren L. Methylphenidate and atomoxetine inhibit social play behavior through prefrontal and subcortical limbic mechanisms in rats. J Neurosci. 2015;35:161-9 pubmed publisher
Finnema S, Hughes Z, Haaparanta Solin M, Stepanov V, Nakao R, VarnÃ¤s K, et al. Amphetamine decreases Î±2C-adrenoceptor binding of [11C]ORM-13070: a PET study in the primate brain. Int J Neuropsychopharmacol. 2014;18: pubmed publisher
Conley J, Meyer J, Nuss A, Doyle T, Savinov S, Hill C, et al. Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti. J Pharmacol Exp Ther. 2015;352:53-60 pubmed publisher
Parker M, Brock A, Sudwarts A, Brennan C. Atomoxetine reduces anticipatory responding in a 5-choice serial reaction time task for adult zebrafish. Psychopharmacology (Berl). 2014;231:2671-9 pubmed publisher
Kobayashi T, Washiyama K, Ikeda K. Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine. Neuropsychopharmacology. 2010;35:1560-9 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2011

SKU :

2011/10

product name :

Tomoxetine hydrochloride

description :

Potent and selective noradrenalin re-uptake inhibitor

target :

Adrenergic Transporter Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at RT

observed molecular weight :

291.82

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Tomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). Displays minimal affinity for a range of other neurotransmitter receptors and transporters (Ki 1 u M). Antidepressant.

product keywords :

Potent selective noradrenaline noradrenalin reuptake inhibitors inhibits Transporters adrenaline adrenalin NET Adrenergic Monoamine Neurotransmitter LY139603 Atomoxetine LY 139603 Adrenergic Transporters 2011,

extended description :

Potent and selective noradrenalin re-uptake inhibitor

chemical name text :

(R)-N-Methyl- -(2-methylphenoxy)-benzenepropanamine hydrochloride

formula :

C17H21NO.HCl

formula text :

C17H21NO.HCl

cas num :

82248-59-7

USD :

243

USD 2025 :

251 USD

product details :

Potent and selective noradrenalin re-uptake inhibitor

alt names :

Atomoxetine,LY 139603

more info or order :

Tocris Bioscience product webpage