product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Tomoxetine hydrochloride
catalog :
2011/10
quantity :
10 mg (also 50 mg)
price :
251 USD
more info or order :
citations: 5
Reference
Achterberg E, van Kerkhof L, Damsteegt R, Trezza V, Vanderschuren L. Methylphenidate and atomoxetine inhibit social play behavior through prefrontal and subcortical limbic mechanisms in rats. J Neurosci. 2015;35:161-9 pubmed publisher
Finnema S, Hughes Z, Haaparanta Solin M, Stepanov V, Nakao R, Varnäs K, et al. Amphetamine decreases α2C-adrenoceptor binding of [11C]ORM-13070: a PET study in the primate brain. Int J Neuropsychopharmacol. 2014;18: pubmed publisher
Conley J, Meyer J, Nuss A, Doyle T, Savinov S, Hill C, et al. Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti. J Pharmacol Exp Ther. 2015;352:53-60 pubmed publisher
Parker M, Brock A, Sudwarts A, Brennan C. Atomoxetine reduces anticipatory responding in a 5-choice serial reaction time task for adult zebrafish. Psychopharmacology (Berl). 2014;231:2671-9 pubmed publisher
Kobayashi T, Washiyama K, Ikeda K. Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine. Neuropsychopharmacology. 2010;35:1560-9 pubmed publisher
product information
brand :
Tocris
catalog number base :
2011
SKU :
2011/10
product name :
Tomoxetine hydrochloride
units size :
10 mg (also 50 mg)
description :
Potent and selective noradrenalin re-uptake inhibitor
target :
Adrenergic Transporter Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
291.82
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
review stars :
4
details of functionality :
Tomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). Displays minimal affinity for a range of other neurotransmitter receptors and transporters (Ki 1 u M). Antidepressant.
top caption :
Potent and selective noradrenalin re-uptake inhibitor
extended description :
Potent and selective noradrenalin re-uptake inhibitor
chemical name text :
(R)-N-Methyl- -(2-methylphenoxy)-benzenepropanamine hydrochloride
formula :
C17H21NO.HCl
formula text :
C17H21NO.HCl
cas num :
82248-59-7
USD :
251 USD
product details :
Potent and selective noradrenalin re-uptake inhibitor
alt names :
Atomoxetine,LY 139603
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK