Halofuginone hydrobromide | Tocris Bioscience 1993/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Halofuginone hydrobromide

catalog :

1993/50

quantity :

50 mg

price :

162 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 1993 - Halofuginone hydrobromide C16H17BrClN3O3.HBr CAS No. 64924-67-0

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1993

SKU :

1993/50

product name :

Halofuginone hydrobromide

description :

High affinity competitive prolyl-tRNA synthetase inhibitor

target :

Synthase/Synthetase Inhibitors

unit size :

50 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

495.59

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Halofuginone hydrobromide is a high affinity competitive prolyl-tRNA synthetase inhibitor (Ki = 18.3 nM). Blocks expression of MMP2. Inhibits ECM invasion in vitro and lung metastasis by bladder cancer cells in mice. Inhibits the development of Th17-driven autoimmunity in a mouse model of multiple sclerosis by activating the amino acid response (AAR) pathway. Also antiparasitic.

product keywords :

High affinity competitive prolyl-tRNA synthetase inhibitors inhibits metastasis MMP2 matrix metalloprotease autoimmunity antiparasitic Other Synthases/Synthetases DNA, RNA and Protein Synthesis 1993,

extended description :

High affinity competitive prolyl-tRNA synthetase inhibitor

chemical name text :

(2R*,3S*)-7-Bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]-4-3H-quinazolinone hydrobromide

formula :

C16H17BrClN3O3.HBr

formula text :

C16H17BrClN3O3.HBr

cas num :

64924-67-0

USD :

160

USD 2025 :

162 USD

product details :

High affinity competitive prolyl-tRNA synthetase inhibitor

more info or order :

Tocris Bioscience product webpage