Leptomycin B | Tocris Bioscience 1987/5 product information

product summary

request information :

company name :

Tocris Bioscience

product type :

chemical

product name :

Leptomycin B

catalog :

1987/5

quantity :

5µg

price :

315 USD

more info or order :

Tocris Bioscience product webpage

product information

CHEMISTRY :

CCC( C=C [C@@H]1OC(=O)C=C[C@@H]1C)=C/[C@H](C)C C=C C(C)=C [C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C C(C)=C C(O)=O

Cat Number :

1987/5

Product Name :

Leptomycin B

Cas Number :

[87081-35-4]

Unit Size :

5µg

Size :

Unit :

µg

USD :

315 USD

Primary Category :

Cell Biology

Secondary Category :

Signal Transduction

Tertiary Category :

Translocation, Exocytosis & Endocytosis

Primary Action :

Inhibits nuclear export of proteins; antitumor

Biological Description :

Antifungal antibiotic that is an inhibitor of the nuclear export of proteins; acts by binding directly to and inhibiting CRM1/exportin-1. Inhibits the nuclear export of the HIV regulatory protein Rev and stabilizes p53. Antitumor in vitro and in vivo.

Formula :

C33H48O6

Molwt :

540.74

Synonyms :

CI 940 LMB

more info or order :

Tocris Bioscience product webpage