product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
Nogo-66 (1-40)
catalog :
1984/1
quantity :
1 mg
price :
469 USD
more info or order :
citations: 1
Reference
Kempf A, Tews B, Arzt M, Weinmann O, Obermair F, Pernet V, et al. The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. PLoS Biol. 2014;12:e1001763 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1984
SKU :
1984/1
product name :
Nogo-66 (1-40)
description :
Competitive antagonist for Nogo-66 receptor; promotes neuron regeneration
target :
Neuronal Metabolism Peptides and Compounds
unit size :
1 mg
category :
Peptides
purity :
95%
storage :
Store at -20°C
observed molecular weight :
4625.16
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Nogo-66 (1-40) is a peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS myelin-induced inhibition of axonal growth, but does not reduce myelin-associated glycoprotein (MAG) inhibition of neurite outgrowth in vitro . Promotes regeneration of hemisected spinal axons and locomotor recovery following spinal injury in vivo .
product keywords :
Competitive antagonists Nogo-66 receptor NGR neuron regeneration NEP140 NEP1-40 Nogo Extracellular Peptide, 1-40 Neuronal Metabolism 1984,
extended description :
Competitive antagonist for Nogo-66 receptor; promotes neuron regeneration
formula :
C206H324N56O65
formula text :
C206H324N56O65
cas num :
475221-20-6
USD :
464
USD 2025 :
469 USD
product details :
Competitive antagonist for Nogo-66 receptor; promotes neuron regeneration
alt names :
NEP1-40,Nogo Extracellular Peptide,1-40
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK