AS 19 | Tocris Bioscience 1968/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AS 19

catalog :

1968/10

quantity :

10 mg (also 50 mg)

price :

291 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Dominguez Soto A, Usategui A, Casas Engel M, Simón Fuentes M, Nieto C, Cuevas V, et al. Serotonin drives the acquisition of a profibrotic and anti-inflammatory gene profile through the 5-HT7R-PKA signaling axis. Sci Rep. 2017;7:14761 pubmed publisher
Majeed Z, Abdeljaber E, Soveland R, Cornwell K, Bankemper A, Koch F, et al. Modulatory Action by the Serotonergic System: Behavior and Neurophysiology in Drosophila melanogaster. Neural Plast. 2016;2016:7291438 pubmed publisher
Watts S, Darios E, Seitz B, Thompson J. 5-HT is a potent relaxant in rat superior mesenteric veins. Pharmacol Res Perspect. 2015;3:e00103 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1968

SKU :

1968/10

product name :

AS 19

description :

Potent 5-HT7 agonist

target :

5-HT7 Receptor Agonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Desiccate at -20°C

observed molecular weight :

283.41

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AS 19 is a potent 5-HT7 receptor agonist (IC50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia in vivo . AS 19 also promotes melanin synthesis in B16F10 murine melanoma cells.

product keywords :

potent 5-HT7 agonists serotonin receptors 5-Hydroxytryptamine agonist AS19 melanogenesis melanin synthesis anti-amnesic 5-HT7 Receptors 1968,

extended description :

Potent 5-HT7 agonist

chemical name text :

(2S)-5-(1,3,5-Trimethylpyrazol-4-yl)-2-(dimethylamino)tetralin

formula :

C18H25N3

formula text :

C18H25N3

cas num :

1000578-26-6

USD :

282

USD 2025 :

291 USD

product details :

Potent 5-HT7 agonist

more info or order :

Tocris Bioscience product webpage