Gossypol | Tocris Bioscience 1964/50 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Gossypol

catalog :

1964/50

quantity :

50 mg

price :

115 USD

citations: 3

Reference
Mani J, Vallo S, Rakel S, Antonietti P, Gessler F, Blaheta R, et al. Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101). BMC Cancer. 2015;15:224 pubmed publisher
Hsiao W, Tsai M, Jow G, Tien L, Lee Y. Involvement of Smac, p53, and caspase pathways in induction of apoptosis by gossypol in human retinoblastoma cells. Mol Vis. 2012;18:2033-42 pubmed
Pang X, Wu Y, Wu Y, Lu B, Chen J, Wang J, et al. (-)-Gossypol suppresses the growth of human prostate cancer xenografts via modulating VEGF signaling-mediated angiogenesis. Mol Cancer Ther. 2011;10:795-805 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1964

SKU :

1964/50

product name :

Gossypol

description :

Proapoptotic; downregulates Bcl-2 and Bcl-XL

target :

Additional Bcl-2 Family Compounds

unit size :

50 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

518.56

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Gossypol is a lipophilic agent derived from cottonseed. Exhibits multiple biological effects including antifertility and anticancer activity. Proapoptotic; downregulates Bcl-2 and Bcl-XL. . R-enantiomer also available.

product keywords :

Pro-apoptotic downregulates Bcl-2 Bcl-XL Bax Mcl-1 Family Bcl-2 Family 1964,

extended description :

Proapoptotic; downregulates Bcl-2 and Bcl-XL

chemical name text :

1,1 ,6,6 ,7,7 -Hexahydroxy-3,3 -dimethyl-5,5 -bis(1-methylethyl)-[2,2 -binaphthalene]-8,8 -dicarboxaldehyde

formula :

C30H30O8

formula text :

C30H30O8

cas num :

303-45-7

USD :

127

USD 2025 :

115 USD

product details :

Proapoptotic; downregulates Bcl-2 and Bcl-XL