SB 408124 | Tocris Bioscience 1963 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 408124

catalog :

1963

quantity :

10 mg

price :

208 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Suo L, Chang X, Zhao Y. The Orexin-A-Regulated Akt/mTOR Pathway Promotes Cell Proliferation Through Inhibiting Apoptosis in Pancreatic Cancer Cells. Front Endocrinol (Lausanne). 2018;9:647 pubmed publisher
Urbańska A, Sokołowska P, Woldan Tambor A, Biegańska K, Brix B, Jöhren O, et al. Orexins/hypocretins acting at Gi protein-coupled OX 2 receptors inhibit cyclic AMP synthesis in the primary neuronal cultures. J Mol Neurosci. 2012;46:10-7 pubmed publisher

product information

brand :

Tocris

master code :

1963

SKU :

1963/10

product name :

SB 408124

description :

Selective non-peptide OX1 antagonist

target :

OX1 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

356.37

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective non-peptide orexin OX1 receptor antagonist (Kb values are 21.7 and 1405 nM for human OX1 and OX2 receptors respectively). Blocks orexin-A induced grooming following oral administration in vivo .

catalog number base :

1963

product keywords :

Selective non-peptide OX1 antagonists Orexin1 Receptors SB408124 GlaxoSmithKline GSK OX1 Receptor 1963,

extended description :

Selective non-peptide OX1 antagonist

chemical name text :

N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N -[4-(dimethylamino)phenyl]urea

formula :

C 19 H 18 F 2 N 4 O

formula text :

C19H18F2N4O

cas num :

288150-92-5

2020 USD :

208

2021 USD :

208 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage