SB 258585 hydrochloride | Tocris Bioscience 1961 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 258585 hydrochloride

catalog :

1961

quantity :

10 mg (also 50 mg)

price :

191 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Sun Y, Yao L, Li L, Wang Y, Du C, Guo Y, et al. Activation and blockade of basolateral amygdala 5-HT6 receptor produce anxiolytic-like behaviors in an experimental model of Parkinson's disease. Neuropharmacology. 2018;137:275-285 pubmed publisher
Yun H, Park K, Hong J, Kim E. Peripheral serotonin-mediated system suppresses bone development and regeneration via serotonin 6 G-protein-coupled receptor. Sci Rep. 2016;6:30985 pubmed publisher
Hampson L, Mackin P, Agius L. Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs. Diabetologia. 2007;50:1743-51 pubmed

product information

brand :

Tocris

master code :

1961

SKU :

1961/10

product name :

SB 258585 hydrochloride

description :

Potent, selective 5-HT6 antagonist

target :

5-HT6 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

523.82

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective 5-HT6 receptor antagonist (pKi = 8.6); displays 160-fold selectivity over other 5-HT receptor subtypes.

catalog number base :

1961

product keywords :

Potent selective 5-HT6 antagonists Serotonin Receptors 5-Hydroxytryptamine SB258585 hydrochloride GlaxoSmithKline GSK 5-HT6 Receptors 1961,

extended description :

Potent, selective 5-HT6 antagonist

chemical name text :

4-Iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamide hydrochloride

formula :

C 18 H 22 IN 3 O 3 S.HCl

formula text :

C18H22IN3O3S.HCl

cas num :

1216468-02-8

2020 USD :

183

2021 USD :

191 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage