product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SB 258585 hydrochloride
catalog :
1961/10
quantity :
10 mg (also 50 mg)
price :
246 USD
more info or order :
Tocris Bioscience product webpage
citations: 3
Reference
Sun Y, Yao L, Li L, Wang Y, Du C, Guo Y, et al. Activation and blockade of basolateral amygdala 5-HT6 receptor produce anxiolytic-like behaviors in an experimental model of Parkinson's disease. Neuropharmacology. 2018;137:275-285 pubmed publisher
Yun H, Park K, Hong J, Kim E. Peripheral serotonin-mediated system suppresses bone development and regeneration via serotonin 6 G-protein-coupled receptor. Sci Rep. 2016;6:30985 pubmed publisher
Hampson L, Mackin P, Agius L. Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs. Diabetologia. 2007;50:1743-51 pubmed
product information
brand :
Tocris
catalog number base :
1961
SKU :
1961/10
product name :
SB 258585 hydrochloride
units size :
10 mg (also 50 mg)
description :
Potent, selective 5-HT6 antagonist
target :
5-HT6 Receptor Antagonists
category :
Small Molecules
purity :
98%
observed molecular weight :
523.82
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SB 258585 hydrochloride is a potent and selective 5-HT6 receptor antagonist (pKi = 8.6); displays 160-fold selectivity over other 5-HT receptor subtypes.
top caption :
Potent, selective 5-HT6 antagonist
extended description :
Potent, selective 5-HT6 antagonist
chemical name text :
4-Iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamide hydrochloride
formula :
C18H22IN3O3S.HCl
formula text :
C18H22IN3O3S.HCl
cas num :
1216468-02-8
USD :
246 USD
product details :
Potent, selective 5-HT6 antagonist
storage :
Store at +4°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK