| Reference |
|---|
Soya S, Takahashi T, McHugh T, Maejima T, Herlitze S, Abe M, et al. Orexin modulates behavioral fear expression through the locus coeruleus. Nat Commun. 2017;8:1606 pubmed publisher |
Chen H, Wang Y, Yang L, Sui J, Hu Z, Hu B. Theta synchronization between medial prefrontal cortex and cerebellum is associated with adaptive performance of associative learning behavior. Sci Rep. 2016;6:20960 pubmed publisher |
Federici L, Caliman I, Molosh A, Fitz S, Truitt W, Bonaventure P, et al. Hypothalamic orexin's role in exacerbated cutaneous vasodilation responses to an anxiogenic stimulus in a surgical menopause model. Psychoneuroendocrinology. 2016;65:127-37 pubmed publisher |
Hsu T, Hahn J, Konanur V, Noble E, Suarez A, Thai J, et al. Hippocampus ghrelin signaling mediates appetite through lateral hypothalamic orexin pathways. elife. 2015;4: pubmed publisher |
Cole S, Mayer H, Petrovich G. Orexin/Hypocretin-1 Receptor Antagonism Selectively Reduces Cue-Induced Feeding in Sated Rats and Recruits Medial Prefrontal Cortex and Thalamus. Sci Rep. 2015;5:16143 pubmed publisher |
Razavi Y, Karimi S, Bani Ardalan M, Haghparast A. Chemical stimulation of the lateral hypothalamus potentiated the sensitization to morphine in rats: involvement of orexin-1 receptor in the ventral tegmental area. EXCLI J. 2014;13:1120-30 pubmed |
Zhou J, Yuan F, Zhang Y, Li D. Upregulation of orexin receptor in paraventricular nucleus promotes sympathetic outflow in obese Zucker rats. Neuropharmacology. 2015;99:481-90 pubmed publisher |
Behrouzvaziri A, Fu D, Tan P, Yoo Y, Zaretskaia M, Rusyniak D, et al. Orexinergic neurotransmission in temperature responses to methamphetamine and stress: mathematical modeling as a data assimilation approach. PLoS ONE. 2015;10:e0126719 pubmed publisher |
Navarro G, Quiroz C, Moreno Delgado D, Sierakowiak A, McDowell K, Moreno E, et al. Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine. J Neurosci. 2015;35:6639-53 pubmed publisher |
Bonnavion P, Jackson A, CARTER M, de Lecea L. Antagonistic interplay between hypocretin and leptin in the lateral hypothalamus regulates stress responses. Nat Commun. 2015;6:6266 pubmed publisher |
Prince C, Rau A, Yorgason J, España R. Hypocretin/Orexin regulation of dopamine signaling and cocaine self-administration is mediated predominantly by hypocretin receptor 1. ACS Chem Neurosci. 2015;6:138-46 pubmed publisher |
Putula J, Pihlajamaa T, Kukkonen J. Calcium affects OX1 orexin (hypocretin) receptor responses by modifying both orexin binding and the signal transduction machinery. Br J Pharmacol. 2014;171:5816-28 pubmed publisher |
Otlivanchik O, Le Foll C, Levin B. Perifornical hypothalamic orexin and serotonin modulate the counterregulatory response to hypoglycemic and glucoprivic stimuli. Diabetes. 2015;64:226-35 pubmed publisher |
Flores A, Valls Comamala V, Costa G, Saravia R, Maldonado R, Berrendero F. The hypocretin/orexin system mediates the extinction of fear memories. Neuropsychopharmacology. 2014;39:2732-41 pubmed publisher |
Karasawa H, Yakabi S, Wang L, TACHE Y. Orexin-1 receptor mediates the increased food and water intake induced by intracerebroventricular injection of the stable somatostatin pan-agonist, ODT8-SST in rats. Neurosci Lett. 2014;576:88-92 pubmed publisher |
Deats S, Adidharma W, Lonstein J, Yan L. Attenuated orexinergic signaling underlies depression-like responses induced by daytime light deficiency. Neuroscience. 2014;272:252-60 pubmed publisher |
Harada S, Yamazaki Y, Koda S, Tokuyama S. Hepatic branch vagus nerve plays a critical role in the recovery of post-ischemic glucose intolerance and mediates a neuroprotective effect by hypothalamic orexin-A. PLoS ONE. 2014;9:e95433 pubmed publisher |
Shu Q, Hu Z, Huang C, Yu X, Fan H, Yang J, et al. Orexin-A promotes cell migration in cultured rat astrocytes via Ca2+-dependent PKCα and ERK1/2 signals. PLoS ONE. 2014;9:e95259 pubmed publisher |
Duncan M, Franklin K, Peng X, Yun C, Legan S. Circadian rhythm disruption by a novel running wheel: roles of exercise and arousal in blockade of the luteinizing hormone surge. Physiol Behav. 2014;131:7-16 pubmed publisher |
Valdivia S, Patrone A, Reynaldo M, Perello M. Acute high fat diet consumption activates the mesolimbic circuit and requires orexin signaling in a mouse model. PLoS ONE. 2014;9:e87478 pubmed publisher |
Chen L, Zhao Y, Zheng D, Ju S, Shen Y, Guo L. Orexin A Affects INS-1 Rat Insulinoma Cell Proliferation via Orexin Receptor 1 and the AKT Signaling Pathway. Int J Endocrinol. 2013;2013:854623 pubmed publisher |
Qi K, Wei C, Li Y, Sui N. Orexin receptors within the nucleus accumbens shell mediate the stress but not drug priming-induced reinstatement of morphine conditioned place preference. Front Behav Neurosci. 2013;7:144 pubmed publisher |
Kay K, Parise E, Lilly N, Williams D. Hindbrain orexin 1 receptors influence palatable food intake, operant responding for food, and food-conditioned place preference in rats. Psychopharmacology (Berl). 2014;231:419-27 pubmed publisher |
Plaza Zabala A, Flores A, Martín García E, Saravia R, Maldonado R, Berrendero F. A role for hypocretin/orexin receptor-1 in cue-induced reinstatement of nicotine-seeking behavior. Neuropsychopharmacology. 2013;38:1724-36 pubmed publisher |
Patyal R, Woo E, Borgland S. Local hypocretin-1 modulates terminal dopamine concentration in the nucleus accumbens shell. Front Behav Neurosci. 2012;6:82 pubmed publisher |
Yi P, Chen Y, Lin C, Chang F. Occurrence of epilepsy at different zeitgeber times alters sleep homeostasis differently in rats. Sleep. 2012;35:1651-65 pubmed publisher |
Feng X, Mi W, Xia F, Mao Ying Q, Jiang J, Xiao S, et al. Involvement of spinal orexin A in the electroacupuncture analgesia in a rat model of post-laparotomy pain. BMC Complement Altern Med. 2012;12:225 pubmed publisher |
Srinivasan S, Simms J, Nielsen C, Lieske S, Bito Onon J, Yi H, et al. The dual orexin/hypocretin receptor antagonist, almorexant, in the ventral tegmental area attenuates ethanol self-administration. PLoS ONE. 2012;7:e44726 pubmed publisher |
Morairty S, Revel F, Malherbe P, Moreau J, Valladao D, Wettstein J, et al. Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone. PLoS ONE. 2012;7:e39131 pubmed publisher |
Adidharma W, Leach G, Yan L. Orexinergic signaling mediates light-induced neuronal activation in the dorsal raphe nucleus. Neuroscience. 2012;220:201-7 pubmed publisher |
Laorden M, Ferenczi S, Pintér Kübler B, González Martín L, Lasheras M, Kovacs K, et al. Hypothalamic orexin--a neurons are involved in the response of the brain stress system to morphine withdrawal. PLoS ONE. 2012;7:e36871 pubmed publisher |
Johnson P, Samuels B, Fitz S, Federici L, Hammes N, Early M, et al. Orexin 1 receptors are a novel target to modulate panic responses and the panic brain network. Physiol Behav. 2012;107:733-42 pubmed publisher |
Johnson P, Samuels B, Fitz S, Lightman S, Lowry C, Shekhar A. Activation of the orexin 1 receptor is a critical component of CO2-mediated anxiety and hypertension but not bradycardia. Neuropsychopharmacology. 2012;37:1911-22 pubmed publisher |
Mahler S, Smith R, Aston Jones G. Interactions between VTA orexin and glutamate in cue-induced reinstatement of cocaine seeking in rats. Psychopharmacology (Berl). 2013;226:687-98 pubmed publisher |
Xu T, Ward R, Pediani J, Milligan G. Intramolecular fluorescence resonance energy transfer (FRET) sensors of the orexin OX1 and OX2 receptors identify slow kinetics of agonist activation. J Biol Chem. 2012;287:14937-49 pubmed publisher |
Riday T, Fish E, Robinson J, Jarrett T, McGuigan M, Malanga C. Orexin-1 receptor antagonism does not reduce the rewarding potency of cocaine in Swiss-Webster mice. Brain Res. 2012;1431:53-61 pubmed publisher |
Tupone D, Madden C, Cano G, Morrison S. An orexinergic projection from perifornical hypothalamus to raphe pallidus increases rat brown adipose tissue thermogenesis. J Neurosci. 2011;31:15944-55 pubmed publisher |
Heydendael W, Sharma K, Iyer V, Luz S, Piel D, Beck S, et al. Orexins/hypocretins act in the posterior paraventricular thalamic nucleus during repeated stress to regulate facilitation to novel stress. Endocrinology. 2011;152:4738-52 pubmed publisher |
Parise E, Lilly N, Kay K, Dossat A, Seth R, Overton J, et al. Evidence for the role of hindbrain orexin-1 receptors in the control of meal size. Am J Physiol Regul Integr Comp Physiol. 2011;301:R1692-9 pubmed publisher |
Shahid I, Rahman A, Pilowsky P. Orexin A in rat rostral ventrolateral medulla is pressor, sympatho-excitatory, increases barosensitivity and attenuates the somato-sympathetic reflex. Br J Pharmacol. 2012;165:2292-303 pubmed publisher |
Rusyniak D, Zaretsky D, Zaretskaia M, DiMicco J. The role of orexin-1 receptors in physiologic responses evoked by microinjection of PgE2 or muscimol into the medial preoptic area. Neurosci Lett. 2011;498:162-6 pubmed publisher |
Shahid I, Rahman A, Pilowsky P. Intrathecal orexin A increases sympathetic outflow and respiratory drive, enhances baroreflex sensitivity and blocks the somato-sympathetic reflex. Br J Pharmacol. 2011;162:961-73 pubmed publisher |
Jerlhag E, Egecioglu E, Dickson S, ENGEL J. Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system. Addict Biol. 2011;16:82-91 pubmed publisher |
Espana R, Oleson E, Locke J, BROOKSHIRE B, Roberts D, Jones S. The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system. Eur J Neurosci. 2010;31:336-48 pubmed publisher |
Malherbe P, Borroni E, Gobbi L, Knust H, Nettekoven M, Pinard E, et al. Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX(2) receptor. Br J Pharmacol. 2009;156:1326-41 pubmed publisher |
Hollander J, Lu Q, Cameron M, Kamenecka T, Kenny P. Insular hypocretin transmission regulates nicotine reward. Proc Natl Acad Sci U S A. 2008;105:19480-5 pubmed publisher |
Gompf H, Aston Jones G. Role of orexin input in the diurnal rhythm of locus coeruleus impulse activity. Brain Res. 2008;1224:43-52 pubmed publisher |
Deng B, Nakamura A, Zhang W, Yanagisawa M, Fukuda Y, Kuwaki T. Contribution of orexin in hypercapnic chemoreflex: evidence from genetic and pharmacological disruption and supplementation studies in mice. J Appl Physiol (1985). 2007;103:1772-9 pubmed |
Sasson R, Dearth R, White R, Chappell P, Mellon P. Orexin A induces GnRH gene expression and secretion from GT1-7 hypothalamic GnRH neurons. Neuroendocrinology. 2006;84:353-63 pubmed |
D Anna K, Gammie S. Hypocretin-1 dose-dependently modulates maternal behaviour in mice. J Neuroendocrinol. 2006;18:553-66 pubmed |
