Ritanserin | Tocris Bioscience 1955 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ritanserin

catalog :

1955

quantity :

10 mg (also 50 mg)

price :

75 USD

more info or order :

Tocris Bioscience product webpage

citations: 7

Reference
Shimizu T, Shimizu S, Wada N, Takai S, Shimizu N, Higashi Y, et al. Brain serotoninergic nervous system is involved in bombesin-induced frequent urination through brain 5-HT7 receptors in rats. Br J Pharmacol. 2017;174:3072-3080 pubmed publisher
Bracha S, Viall A, Goodall C, Stang B, Ruaux C, Seguin B, et al. The expression and role of serotonin receptor 5HTR2A in canine osteoblasts and an osteosarcoma cell line. BMC Vet Res. 2013;9:251 pubmed publisher
Jahchan N, Dudley J, Mazur P, Flores N, Yang D, Palmerton A, et al. A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer Discov. 2013;3:1364-77 pubmed publisher
Mondal A, Aizawa S, Sakata I, Goswami C, Oda S, Sakai T. Mechanism of ghrelin-induced gastric contractions in Suncus murinus (house musk shrew): involvement of intrinsic primary afferent neurons. PLoS ONE. 2013;8:e60365 pubmed publisher
Chen Y, Okano K, Maeda T, Chauhan V, Golczak M, Maeda A, et al. Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration. J Biol Chem. 2012;287:5059-69 pubmed publisher
Alsene K, Bakshi V. Pharmacological stimulation of locus coeruleus reveals a new antipsychotic-responsive pathway for deficient sensorimotor gating. Neuropsychopharmacology. 2011;36:1656-67 pubmed publisher
Hampson L, Mackin P, Agius L. Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs. Diabetologia. 2007;50:1743-51 pubmed

product information

brand :

Tocris

master code :

1955

SKU :

1955/10

product name :

Ritanserin

description :

Potent 5-HT2 antagonist

target :

Non-selective 5-HT2 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

477.57

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and long-acting 5-HT2 receptor antagonist (Ki = 0.39 nM). Anxiolytic in vivo .

catalog number base :

1955

product keywords :

Potent 5-HT2 antagonists Non-Selective Serotonin Receptors Non-selective 5-HT2 1955,

extended description :

Potent 5-HT2 antagonist

chemical name text :

6-[2-[4-[Bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one

formula :

C 27 H 25 F 2 N 3 OS

formula text :

C27H25F2N3OS

cas num :

87051-43-2

2020 USD :

2021 USD :

75 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage