product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
m-3M3FBS
catalog :
1941/10
quantity :
10 mg
price :
177 USD
more info or order :
citations: 10
Reference
Carim S, Ben El Kadhi K, Yan G, Sweeney S, Hickson G, Carreno S, et al. IPIP27 Coordinates PtdIns(4,5)P2 Homeostasis for Successful Cytokinesis. Curr Biol. 2019;: pubmed publisher
Zhang S, Duan L, He S, Zhuang G, Yu X. Phosphatidylinositol 3,4-bisphosphate regulates neurite initiation and dendrite morphogenesis via actin aggregation. Cell Res. 2017;27:253-273 pubmed publisher
Shutov L, Warwick C, Shi X, Gnanasekaran A, Shepherd A, Mohapatra D, et al. The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1. J Neurosci. 2016;36:5055-70 pubmed publisher
Shambharkar P, Bittinger M, Latario B, Xiong Z, Bandyopadhyay S, Davis V, et al. TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis. PLoS ONE. 2015;10:e0127480 pubmed publisher
Rioult Pedotti M, Pekanovic A, Atiemo C, Marshall J, Luft A. Dopamine Promotes Motor Cortex Plasticity and Motor Skill Learning via PLC Activation. PLoS ONE. 2015;10:e0124986 pubmed publisher
Semple Rowland S, Madorsky I, Bolch S, Berry J, Smith W. Activation of phospholipase C mimics the phase shifting effects of light on melatonin rhythms in retinal photoreceptors. PLoS ONE. 2013;8:e83378 pubmed publisher
Hutchins B, Klenke U, Wray S. Calcium release-dependent actin flow in the leading process mediates axophilic migration. J Neurosci. 2013;33:11361-71 pubmed publisher
Lee G, Subramanian N, Kim A, Aksentijevich I, Goldbach Mansky R, Sacks D, et al. The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. Nature. 2012;492:123-7 pubmed publisher
Okada Y, Imendra K, Miyazaki T, Hotokezaka H, Fujiyama R, Toda K. High extracellular Ca2+ stimulates Ca2+-activated Cl- currents in frog parathyroid cells through the mediation of arachidonic acid cascade. PLoS ONE. 2011;6:e19158 pubmed publisher
Krjukova J, Holmqvist T, Danis A, Akerman K, Kukkonen J. Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation. Br J Pharmacol. 2004;143:3-7 pubmed
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1941
SKU :
1941/10
product name :
m-3M3FBS
description :
Phospholipase C activator
target :
Phospholipase Activators
unit size :
10 mg
category :
Small Molecules
purity :
98%
storage :
Store at RT
observed molecular weight :
343.36
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
m -3M3FBS is an activator of phospholipase C (PLC). Stimulates superoxide generation, Ca2+ release and inositol phosphate formation in a variety of cell types. Also inhibits growth of the leukemic cell lines U937 and THP-1. . Negative Control also available.
product keywords :
Phospholipases C activators activates PLC esterases Phospholipases Phospholipase C Enzyme Substrates/ Activators 1941,
extended description :
Phospholipase C activator
chemical name text :
2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
formula :
C16H16F3NO2S
formula text :
C16H16F3NO2S
cas num :
200933-14-8
USD :
171
USD 2025 :
177 USD
product details :
Phospholipase C activator
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK