chemical

Damnacanthal

1936

1 mg

175 USD

1936

1936/1

Damnacanthal

Potent, selective p56lck inhibitor; also LIMK1/2 inhibitor

Src Family Kinase Inhibitors

Small Molecules

1 mg

98%

282.25

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Potent inhibitor of p56lck tyrosine kinase activity (IC50 = 17 nM for inhibition of autophosphorylation). Displays 7- to 20-fold selectivity over p59fyn and p60src tyrosine kinases, 40-fold selectivity over c-ErbB2, EGF- and insulin-receptor tyrosine kinases, and 100-fold selectivity over PKA and PKC. Mobilizes intracellular Ca2+ in dermal fibroblasts and inhibits Ras function. Also inhibits LIMK1/2, as well as migration and invasion of breast cancer cells in vitro .

1936

potent inhibitors inhibits p56lck kinases selective Src Kinases LIMK 1936,

Potent, selective p56lck inhibitor; also LIMK1/2 inhibitor

9,10-Dihydroxy-3-hydroxy-1-methoxy-9,10-dioxo-2-anthracenecarboxaldehyde

C 16 H 10 O 5

C16H10O5

477-84-9

175

175 USD

Store at -20°C