Damnacanthal | Tocris Bioscience 1936/1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Damnacanthal

catalog :

1936/1

quantity :

1 mg

price :

193 USD

product information

brand :

Tocris

master code :

1936

SKU :

1936/1

product name :

Damnacanthal

unit size :

1 mg

description :

The Recombinant Human Complement Component C2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Complement Component C2 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Src Family Kinase Inhibitors

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

282.25

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Damnacanthal is a potent inhibitor of p56lck tyrosine kinase activity (IC50 = 17 nM for inhibition of autophosphorylation). Displays 7- to 20-fold selectivity over p59fyn and p60src tyrosine kinases, 40-fold selectivity over c-ErbB2, EGF- and insulin-receptor tyrosine kinases, and 100-fold selectivity over PKA and PKC. Mobilizes intracellular Ca2+ in dermal fibroblasts and inhibits Ras function. Also inhibits LIMK1/2, as well as migration and invasion of breast cancer cells in vitro .

extended description :

Potent, selective p56lck inhibitor; also LIMK1/2 inhibitor

chemical name text :

9,10-Dihydroxy-3-hydroxy-1-methoxy-9,10-dioxo-2-anthracenecarboxaldehyde

formula :

C 16 H 10 O 5

formula text :

C16H10O5

cas num :

477-84-9

USD :

182

Jul-22 :

193 USD

product details :

Potent, selective p56lck inhibitor; also LIMK1/2 inhibitor

sizes available :

1 mg