Exendin-4 | Tocris Bioscience 1933 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Exendin-4

catalog :

1933

quantity :

1 mg

price :

393 USD

more info or order :

Tocris Bioscience product webpage

citations: 8

Reference
Jesinkey S, Madiraju A, Alves T, Yarborough O, Cardone R, Zhao X, et al. Mitochondrial GTP Links Nutrient Sensing to β Cell Health, Mitochondrial Morphology, and Insulin Secretion Independent of OxPhos. Cell Rep. 2019;28:759-772.e10 pubmed publisher
Vallöf D, Vestlund J, Jerlhag E. Glucagon-like peptide-1 receptors within the nucleus of the solitary tract regulate alcohol-mediated behaviors in rodents. Neuropharmacology. 2019;149:124-132 pubmed publisher
Lutter M, Bahl E, Hannah C, Hofammann D, Acevedo S, Cui H, et al. Novel and ultra-rare damaging variants in neuropeptide signaling are associated with disordered eating behaviors. PLoS ONE. 2017;12:e0181556 pubmed publisher
Watson L, Tsai L. Molecular biology: Local metabolites linked to memory. Nature. 2017;546:361-362 pubmed publisher
Tuesta L, Chen Z, Duncan A, Fowler C, Ishikawa M, Lee B, et al. GLP-1 acts on habenular avoidance circuits to control nicotine intake. Nat Neurosci. 2017;20:708-716 pubmed publisher
Suissa Y, Magenheim J, Stolovich Rain M, Hija A, Collombat P, Mansouri A, et al. Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas. PLoS ONE. 2013;8:e70397 pubmed publisher
Wang D, Luo P, Wang Y, Li W, Wang C, Sun D, et al. Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism. Diabetes. 2013;62:1697-708 pubmed publisher
Pritchett C, Hajnal A. Glucagon-like peptide-1 regulation of carbohydrate intake is differentially affected by obesogenic diets. Obesity (Silver Spring). 2012;20:313-7 pubmed publisher

product information

brand :

Tocris

master code :

1933

SKU :

1933/1

product name :

Exendin-4

description :

Potent GLP-1 receptor agonist

target :

Glucagon-Like Peptide 1 Receptor Agonists

category :

Peptides

unit size :

1 mg

observed molecular weight :

4186.61

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

High affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM); originally isolated from Heloderma suspectum venom. Potently induces cAMP formation without stimulating amylase release in pancreatic acini. Potentiates glucose-induced insulin secretion in isolated rat islets. Protects against glutamate-induced neurotoxicity.

catalog number base :

1933

product keywords :

Potent GLP-1 receptor agonists Receptors Glucagon-Like Peptide 1 AC2993 Ex4 Exenatide AC 2993 Glucagon-Like Peptide 1 Receptors 1933,

extended description :

Potent GLP-1 receptor agonist

formula :

C 184 H 282 N 50 O 60 S

formula text :

C184H282N50O60S

cas num :

141758-74-9

2020 USD :

374

2021 USD :

393 USD

alt names :

Exenatide, AC 2993

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage