product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
[D-Lys3]-GHRP-6
catalog :
1922/5
quantity :
5 mg
price :
190 USD
more info or order :
citations: 9
Reference
Murtuza M, Isokawa M. Endogenous ghrelin-O-acyltransferase (GOAT) acylates local ghrelin in the hippocampus. J Neurochem. 2018;144:58-67 pubmed publisher
Mao Y, Li Z, Chen K, Yu H, Zhang S, Jiang M, et al. Antinociceptive Effect of Ghrelin in a Rat Model of Irritable Bowel Syndrome Involves TRPV1/Opioid Systems. Cell Physiol Biochem. 2017;43:518-530 pubmed publisher
Hashiguchi H, Sheng Z, Routh V, Gerzanich V, Simard J, Bryan J. Direct versus indirect actions of ghrelin on hypothalamic NPY neurons. PLoS ONE. 2017;12:e0184261 pubmed publisher
Kamei J, Hayashi S, Sakai A, Nakanishi Y, Kai M, Ikegami M, et al. Rikkunshito prevents paclitaxel-induced peripheral neuropathy through the suppression of the nuclear factor kappa B (NFκB) phosphorylation in spinal cord of mice. PLoS ONE. 2017;12:e0171819 pubmed publisher
Gomez J, Ryabinin A. The effects of ghrelin antagonists [D-Lys(3) ]-GHRP-6 or JMV2959 on ethanol, water, and food intake in C57BL/6J mice. Alcohol Clin Exp Res. 2014;38:2436-44 pubmed publisher
Torres Fuentes C, Theeuwes W, McMullen M, McMullen A, Dinan T, Cryan J, et al. Devil's Claw to suppress appetite--ghrelin receptor modulation potential of a Harpagophytum procumbens root extract. PLoS ONE. 2014;9:e103118 pubmed publisher
Haam J, Halmos K, Di S, Tasker J. Nutritional state-dependent ghrelin activation of vasopressin neurons via retrograde trans-neuronal-glial stimulation of excitatory GABA circuits. J Neurosci. 2014;34:6201-13 pubmed publisher
Song L, Zhu Q, Liu T, Yu M, Xiao K, Kong Q, et al. Ghrelin modulates lateral amygdala neuronal firing and blocks acquisition for conditioned taste aversion. PLoS ONE. 2013;8:e65422 pubmed publisher
Kemp B, Howell N, Gray J, Keller S, NASS R, Padia S. Intrarenal ghrelin infusion stimulates distal nephron-dependent sodium reabsorption in normal rats. Hypertension. 2011;57:633-9 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1922
SKU :
1922/5
product name :
[D-Lys3]-GHRP-6
description :
Ghrelin receptor antagonist
target :
Ghrelin Receptor Antagonists
unit size :
5 mg
category :
Peptides
purity :
95%
storage :
Store at -20°C
observed molecular weight :
930.12
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
[D-Lys3]-GHRP-6 is an antagonist at the ghrelin receptor (GHS-R1a) (IC50 = 0.9 u M). Also weakly binds to melanocortin receptors (Ki = 26-120 u M). Centrally active in vivo .
product keywords :
Ghrelin receptors antagonists GHS-R1a Growth Hormone Secretagog 1a Ghrelin Receptors 1922,
extended description :
Ghrelin receptor antagonist
formula :
C49H63N13O6
formula text :
C49H63N13O6
cas num :
136054-22-3
USD :
188
USD 2025 :
190 USD
product details :
Ghrelin receptor antagonist
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK