product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
PKA Inhibitor Fragment (6-22) amide
catalog :
1904/1
quantity :
1 mg
price :
241 USD
more info or order :
citations: 7
Reference
Costa L, Sardone L, Bonaccorso C, D Antoni S, Spatuzza M, Gulisano W, et al. Activation of Serotonin 5-HT7 Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X Syndrome. Front Mol Neurosci. 2018;11:353 pubmed publisher
O Neill N, Sylantyev S. Feature Article: Selective modulation of tonically active GABAA receptor functional subgroups by G-proteins and protein kinase C. Exp Biol Med (Maywood). 2018;243:1046-1055 pubmed publisher
Cui Y, Prokin I, Xu H, Delord B, Genet S, Venance L, et al. Endocannabinoid dynamics gate spike-timing dependent depression and potentiation. elife. 2016;5:e13185 pubmed publisher
Pleil K, Rinker J, Lowery Gionta E, Mazzone C, McCall N, Kendra A, et al. NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking. Nat Neurosci. 2015;18:545-52 pubmed publisher
Caiati M, Safiulina V, Fattorini G, Sivakumaran S, Legname G, Cherubini E. PrPC controls via protein kinase A the direction of synaptic plasticity in the immature hippocampus. J Neurosci. 2013;33:2973-83 pubmed publisher
Tumati S, Yamamura H, Vanderah T, Roeske W, Varga E. Sustained morphine treatment augments capsaicin-evoked calcitonin gene-related peptide release from primary sensory neurons in a protein kinase A- and Raf-1-dependent manner. J Pharmacol Exp Ther. 2009;330:810-7 pubmed publisher
Hopf F, Mailliard W, Gonzalez G, Diamond I, Bonci A. Atypical protein kinase C is a novel mediator of dopamine-enhanced firing in nucleus accumbens neurons. J Neurosci. 2005;25:985-9 pubmed
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1904
SKU :
1904/1
product name :
PKA Inhibitor Fragment (6-22) amide
description :
Potent protein kinase A inhibitor
target :
Protein Kinase A Inhibitors
unit size :
1 mg
category :
Peptides
purity :
95%
storage :
Store at -20°C
observed molecular weight :
1868.08
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
PKA inhibitor fragment (6-22) amide is a potent inhibitor of cAMP-dependent protein kinase (PKA) (Ki = 2.5 nM); derived from the active portion of the heat-stable PKA inhibitor protein PKI.
product keywords :
Potent protein kinases A inhibitors inhibits PKA Protein kinase inhibitor-(6-22)-amide PKI-(6-22)-amide Protein Kinase A 1904,
extended description :
Potent protein kinase A inhibitor
formula :
C80H130N28O24
formula text :
C80H130N28O24
cas num :
121932-06-7
USD :
238
USD 2025 :
241 USD
product details :
Potent protein kinase A inhibitor
alt names :
Protein kinase inhibitor-(6-22)-amide,PKI-(6-22)-amide
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK