product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
BTS
catalog :
1870/10
quantity :
10 mg
price :
197 USD
more info or order :
citations: 5
Reference
Ferreira F, Raghunathan V, Luxardi G, Zhu K, Zhao M. Early redox activities modulate Xenopus tail regeneration. Nat Commun. 2018;9:4296 pubmed publisher
Magown P, Shettar B, Zhang Y, Rafuse V. Direct optical activation of skeletal muscle fibres efficiently controls muscle contraction and attenuates denervation atrophy. Nat Commun. 2015;6:8506 pubmed publisher
Lee C, Dagnino Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, et al. Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function. Skelet Muscle. 2015;5:4 pubmed publisher
Thorne N, Shen M, Lea W, Simeonov A, Lovell S, Auld D, et al. Firefly luciferase in chemical biology: a compendium of inhibitors, mechanistic evaluation of chemotypes, and suggested use as a reporter. Chem Biol. 2012;19:1060-72 pubmed publisher
Boncompagni S, Loy R, Dirksen R, Franzini Armstrong C. The I4895T mutation in the type 1 ryanodine receptor induces fiber-type specific alterations in skeletal muscle that mimic premature aging. Aging Cell. 2010;9:958-70 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1870
SKU :
1870/10
product name :
BTS
description :
Selective inhibitor of skeletal muscle myosin II ATPase activity
target :
Myosin Inhibitors
unit size :
10 mg
category :
Small Molecules
purity :
99%
storage :
Desiccate at RT
observed molecular weight :
261.34
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
BTS is a selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.
product keywords :
Selective inhibitors inhibits skeletal muscle myosin II ATPase activity Myosin 1870,
extended description :
Selective inhibitor of skeletal muscle myosin II ATPase activity
chemical name text :
4-Methyl-N-(phenylmethyl)benzenesulfonamide
formula :
C14H15NO2S
formula text :
C14H15NO2S
cas num :
1576-37-0
USD :
191
USD 2025 :
197 USD
product details :
Selective inhibitor of skeletal muscle myosin II ATPase activity
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK