NSC 663284 | Tocris Bioscience 1867 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NSC 663284

catalog :

1867

quantity :

10 mg

price :

257 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

1867

SKU :

1867/10

product name :

NSC 663284

description :

Potent, selective Cdc25 phosphatase inhibitor

target :

Cdc25 Phosphatase Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

99%

observed molecular weight :

321.76

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, selective inhibitor of Cdc25 dual specificity phosphatases (Ki values are 29, 95 and 89 nM for human Cdc25A, Cdc25B2 and Cdc25C respectively); 20- and 450-fold selective over VHR and PTP1B phosphatases respectively. Arrests cells at both G1 and G2/M phase and blocks cdk2 and cdk1 activation. Blocks proliferation of a range of human tumor cell lines (IC50 = 0.2 - 35 u M).

catalog number base :

1867

product keywords :

Potent selective Cdc25 phosphatase inhibitors inhibits Cyclin-Dependent Protein Kinase Cdk Kinases Dual-Specificity Phosphatases NSC663284 Cdc25 Phosphatase Cyclin-dependent Kinase 1867,

extended description :

Potent, selective Cdc25 phosphatase inhibitor

chemical name text :

6-Chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione

formula :

C 15 H 16 ClN 3 O 3

formula text :

C15H16ClN3O3

cas num :

383907-43-5

2020 USD :

249

2021 USD :

257 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage