L-165,041 | Tocris Bioscience 1856 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

L-165,041

catalog :

1856

quantity :

10 mg (also 50 mg)

price :

185 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Martin Martin N, Zabala Letona A, Fernandez Ruiz S, Arreal L, Camacho L, Castillo Martin M, et al. PPARδ Elicits Ligand-Independent Repression of Trefoil Factor Family to Limit Prostate Cancer Growth. Cancer Res. 2018;78:399-409 pubmed publisher
Mottillo E, Bloch A, Leff T, Granneman J. Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply. J Biol Chem. 2012;287:25038-48 pubmed publisher

product information

brand :

Tocris

master code :

1856

SKU :

1856/10

product name :

L-165,041

description :

Potent PPAR agonist

target :

PPAR delta Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

402.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent PPAR agonist (Ki = 6 nM); displays 100-fold selectivity for both mouse and human PPAR receptors over other subtypes. Raises plasma cholesterol levels in vivo , in insulin-resistant db/db mice. Neuroprotective in models of cerebral infarction and Parkinson s disease.

catalog number base :

1856

product keywords :

Potent PPAR PPARdelta agonists Peroxisome Proliferator-Activating Receptors agonist L165041 PPARdelta Receptors 1856,

extended description :

Potent PPAR agonist

chemical name text :

[4-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]acetic acid

formula :

C 22 H 26 O 7

formula text :

C22H26O7

cas num :

79558-09-1

2020 USD :

185

2021 USD :

185 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage