L-165,041 | Tocris Bioscience 1856/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

L-165,041

catalog :

1856/10

quantity :

10 mg (also 50 mg)

price :

231 USD

citations: 2

Reference
Martin Martin N, Zabala Letona A, Fernandez Ruiz S, Arreal L, Camacho L, Castillo Martin M, et al. PPARδ Elicits Ligand-Independent Repression of Trefoil Factor Family to Limit Prostate Cancer Growth. Cancer Res. 2018;78:399-409 pubmed publisher
Mottillo E, Bloch A, Leff T, Granneman J. Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply. J Biol Chem. 2012;287:25038-48 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

1856

SKU :

1856/10

product name :

L-165,041

Description :

Potent PPAR agonist

target :

PPAR delta Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

402.44

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

L-165,041 is a potent PPAR agonist (Ki = 6 nM); displays 100-fold selectivity for both mouse and human PPAR receptors over other subtypes. Raises plasma cholesterol levels in vivo , in insulin-resistant db/db mice. Neuroprotective in models of cerebral infarction and Parkinson s disease.

extended description :

Potent PPAR agonist

chemical name text :

[4-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]acetic acid

formula :

C 22 H 26 O 7

formula text :

C22H26O7

cas num :

79558-09-1

USD :

231 USD

product details :

Potent PPAR agonist

storage :

Desiccate at RT