product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Ac2-26
catalog :
1845
quantity :
500 ug
price :
252 USD
more info or order :
citations: 6
Reference
Pessolano E, Belvedere R, Bizzarro V, Franco P, Marco I, Petrella F, et al. Annexin A1 Contained in Extracellular Vesicles Promotes the Activation of Keratinocytes by Mesoglycan Effects: An Autocrine Loop Through FPRs. Cells. 2019;8: pubmed publisher
Fredman G, Kamaly N, Spolitu S, Milton J, Ghorpade D, Chiasson R, et al. Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice. Sci Transl Med. 2015;7:275ra20 pubmed publisher
Leoni G, Neumann P, Kamaly N, Quirós M, Nishio H, Jones H, et al. Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest. 2015;125:1215-27 pubmed publisher
Leoni G, Gripentrog J, Lord C, Riesselman M, Sumagin R, Parkos C, et al. Human neutrophil formyl peptide receptor phosphorylation and the mucosal inflammatory response. J Leukoc Biol. 2015;97:87-101 pubmed publisher
Dalli J, Montero Melendez T, McArthur S, Perretti M. Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils. Front Pharmacol. 2012;3:28 pubmed publisher
Brancaleone V, Dalli J, Bena S, Flower R, Cirino G, Perretti M. Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature. J Immunol. 2011;186:4905-14 pubmed publisher
product information
brand :
Tocris
master code :
1845
SKU :
1845/500U
product name :
Ac2-26
description :
Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation
target :
Cell Adhesion Inhibitors
category :
Peptides
unit size :
500 ug
observed molecular weight :
3089.46
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Annexin/lipocortin 1-mimetic peptide; inhibits leukocyte extravasation. Reduces neutrophil adhesion and emigration, promotes detachment of neutrophils from activated mesenteric endothelium and accelerates epithelial wound repair after induced colonic injury in mice in vivo . Anti-inflammatory.
catalog number base :
1845
product keywords :
Annexin lipocortin 1-mimetic inhibits inhibitors leukocyte extravasation Adhesion Molecules Cell Adhesion Molecules 1845,
extended description :
Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation
formula :
C 141 H 210 N 32 O 44 S
formula text :
C141H210N32O44S
cas num :
151988-33-9
2020 USD :
247
2021 USD :
252 USD
storage :
Desiccate at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK