product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CYN 154806
catalog :
1843/1
quantity :
1 mg
price :
345 USD
more info or order :
citations: 9
Reference
Lavogina D, Laasfeld T, Vardja M, Lust H, Jaal J. Viability fingerprint of glioblastoma cell lines: roles of mitotic, proliferative, and epigenetic targets. Sci Rep. 2021;11:20338 pubmed publisher
Bowman B, Bokiniec P, McMullan S, Goodchild A, Burke P. Somatostatin 2 Receptors in the Spinal Cord Tonically Restrain Thermogenic, Cardiac and Other Sympathetic Outflows. Front Neurosci. 2019;13:121 pubmed publisher
Hastoy B, Godazgar M, Clark A, Nylander V, Spiliotis I, van de Bunt M, et al. Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells. Sci Rep. 2018;8:16994 pubmed publisher
Paramonov V, Desai D, Kettiger H, Mamaeva V, Rosenholm J, Sahlgren C, et al. Targeting Somatostatin Receptors By Functionalized Mesoporous Silica Nanoparticles - Are We Striking Home?. Nanotheranostics. 2018;2:320-346 pubmed publisher
Elliott A, Ustione A, Piston D. Somatostatin and insulin mediate glucose-inhibited glucagon secretion in the pancreatic α-cell by lowering cAMP. Am J Physiol Endocrinol Metab. 2015;308:E130-43 pubmed publisher
Iwagaki N, Garzillo F, Polgár E, Riddell J, Todd A. Neurochemical characterisation of lamina II inhibitory interneurons that express GFP in the PrP-GFP mouse. Mol Pain. 2013;9:56 pubmed publisher
Spitsin S, Tuluc F, Meshki J, Ping Lai J, Tustin Iii R, Douglas S. Analog of somatostatin vapreotide exhibits biological effects in vitro via interaction with neurokinin-1 receptor. Neuroimmunomodulation. 2013;20:247-55 pubmed publisher
Yang N, Liu S, Zheng L, Ji T, Li Y, Mi X, et al. Activation of submucosal 5-HT(3) receptors elicits a somatostatin-dependent inhibition of ion secretion in rat colon. Br J Pharmacol. 2010;159:1623-5 pubmed publisher
Foong J, Parry L, Gwynne R, Bornstein J. 5-HT(1A), SST(1), and SST(2) receptors mediate inhibitory postsynaptic potentials in the submucous plexus of the guinea pig ileum. Am J Physiol Gastrointest Liver Physiol. 2010;298:G384-94 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1843
SKU :
1843/1
product name :
CYN 154806
description :
Selective sst2 antagonist
target :
Somatostatin Receptor Antagonists
unit size :
1 mg
category :
Peptides
purity :
95%
storage :
Store at -20°C
observed molecular weight :
1197.35
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
CYN 154806 is a potent and selective somatostatin sst2 receptor antagonist. pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively.
product keywords :
Selective sst2 antagonists Receptors Somatostatin CYN154806 Somatostatin Receptors 1843,
extended description :
Selective sst2 antagonist
formula :
C56H68N12O14S2
formula text :
C56H68N12O14S2
cas num :
183658-72-2
USD :
331
USD 2025 :
345 USD
product details :
Selective sst2 antagonist
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK