Fostriecin sodium salt | Tocris Bioscience 1840/50 product information

product summary

request information :

company name :

Tocris Bioscience

product type :

chemical

product name :

Fostriecin sodium salt

catalog :

1840/50

quantity :

50µg

price :

255 USD

more info or order :

Tocris Bioscience product webpage

product information

CHEMISTRY :

[Na+].C[C@@](O)( C=C [C@H]1CC=CC(=O)O1)[C@@H](C[C@@H](O) C=C/C=C C=C CO)OP(O)([O-])=O

Cat Number :

1840/50

Product Name :

Fostriecin sodium salt

Cas Number :

[87860-39-7]

Unit Size :

50µg

Size :

Unit :

µg

USD :

255 USD

Primary Category :

Enzymes

Secondary Category :

Phosphatases

Tertiary Category :

Protein Ser/Thr Phosphatase

Primary Action :

Potent PP2A and PP4 inhibitor

Biological Description :

Originally identified as an antitumor antibiotic from Streptomyces pulveraceous. Displays potent inhibition of protein phosphatase types 2A (PP2A) and 4 (PP4) with IC50 values of 1.5 nM and 3 nM respectively. Also exhibits weaker inhibition of topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM) with no apparent inhibition of protein phosphatase type 2B (PP2B). Active in vivo.

Formula :

C19H26O9PNa

Molwt :

452.37

more info or order :

Tocris Bioscience product webpage