IRL-2500 | Tocris Bioscience 1838 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

IRL-2500

catalog :

1838

quantity :

10 mg

price :

280 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Merlen C, Farhat N, Luo X, Chatenet D, Tadevosyan A, Villeneuve L, et al. Intracrine endothelin signaling evokes IP3-dependent increases in nucleoplasmic Ca²? in adult cardiac myocytes. J Mol Cell Cardiol. 2013;62:189-202 pubmed publisher

product information

brand :

Tocris

master code :

1838

SKU :

1838/10

product name :

IRL-2500

description :

Potent ETB antagonist

target :

Endothelin ETB Receptor Antagonists

category :

Small Molecules

unit size :

10 mg

purity :

99%

observed molecular weight :

573.69

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent endothelin receptor antagonist; shows some selectivity for ETB receptors (IC50 values are 1.3 and 94 nM for ETB and ETA receptors respectively). Inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo .

catalog number base :

1838

product keywords :

Potent ETB antagonists Receptors Endothelin IRL2500 Endothelin ETB Receptors 1838,

extended description :

Potent ETB antagonist

chemical name text :

N-3-[1,1 -Biphenyl]-4-yl-N-(3,5-dimethylbenzoyl)-N-methyl-D-alanyl-L-tryptophan

formula :

C 36 H 35 N 3 O 4

formula text :

C36H35N3O4

cas num :

169545-27-1

2020 USD :

271

2021 USD :

280 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage