product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
HS 014
catalog :
1831
quantity :
1 mg
price :
352 USD
more info or order :
citations: 1
Reference
Panaro B, Tough I, Engelstoft M, Matthews R, Digby G, Møller C, et al. The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo. Cell Metab. 2014;20:1018-29 pubmed publisher
product information
brand :
Tocris
master code :
1831
SKU :
1831/1
product name :
HS 014
description :
Selective MC4 receptor antagonist
target :
Melanocortin Receptor Antagonists
category :
Peptides
unit size :
1 mg
observed molecular weight :
1563.77
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and nociception in mice following central administration in vivo . Also inhibits IL-1 -induced Fos expression in the paraventricular hypothalamus.
catalog number base :
1831
product keywords :
Selective MC4R receptor antagonists Receptors Melanocortin HS014 Melanocortin Receptors 1831,
extended description :
Selective MC4 receptor antagonist
formula :
C 71 H 94 N 20 O 17 S 2
formula text :
C71H94N20O17S2
cas num :
207678-81-7
2020 USD :
338
2021 USD :
352 USD
storage :
Desiccate at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK