HS 014 | Tocris Bioscience 1831/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

HS 014

catalog :

1831/1

quantity :

1 mg

price :

442 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Avegno E, Lobell T, Itoga C, Baynes B, Whitaker A, Weera M, et al. Central Amygdala Circuits Mediate Hyperalgesia in Alcohol-Dependent Rats. J Neurosci. 2018;38:7761-7773 pubmed publisher
Panaro B, Tough I, Engelstoft M, Matthews R, Digby G, MÃ¸ller C, et al. The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo. Cell Metab. 2014;20:1018-29 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1831

SKU :

1831/1

product name :

HS 014

description :

Selective MC4 receptor antagonist

target :

Melanocortin Receptor Antagonists

unit size :

1 mg

category :

Peptides

purity :

95%

storage :

Store at -20°C

observed molecular weight :

1563.77

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

HS 014 is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and nociception in mice following central administration in vivo . Also inhibits IL-1 -induced Fos expression in the paraventricular hypothalamus.

product keywords :

Selective MC4R receptor antagonists Receptors Melanocortin HS014 Melanocortin Receptors 1831,

extended description :

Selective MC4 receptor antagonist

formula :

C71H94N20O17S2

formula text :

C71H94N20O17S2

cas num :

207678-81-7

USD :

437

USD 2025 :

442 USD

product details :

Selective MC4 receptor antagonist

more info or order :

Tocris Bioscience product webpage