Indirubin-3'-oxime | Tocris Bioscience 1813 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Indirubin-3'-oxime

catalog :

1813

quantity :

10 mg (also 50 mg)

price :

189 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

1813

SKU :

1813/10

product name :

Indirubin-3'-oxime

description :

GSK-3 inhibitor; also inhibits cdks and other protein kinases

target :

GSK-3 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

277.28

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of GSK-3 (IC50 = 190 nM) and cyclin dependent kinases (cdks; IC50 values are 0.05, 0.18 and 0.25-0.5 M for cdk9, cdk1 and cdk2, respectively). Also reported to inhibit AMPK, LCK and SGK. Inhibits cdk5- and GSK-3 -mediated tau phosphorylation. Induces cell cycle arrest and inhibits cell proliferation.

catalog number base :

1813

product keywords :

Protein kinase GSK-3 GSK-3beta inhibits inhibitors kinases Cyclin-dependent Induces cell cycle arrest antiproliferative Broad Spectrum GSK Glycogen Synthase 3 Cdk Cyclin-Dependent Carbohydrate Metabolism Cell Cycle Indirubin-3-oxime Indirubin-3-mono Indirubin-3'-monoxime Glycogen Synthase Kinase 3 Cyclin-dependent Kinase Cell Cycle Inhibitors Glycogen Synthase Kinase 1813,

extended description :

GSK-3 inhibitor; also inhibits cdks and other protein kinases

chemical name text :

3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one

formula :

C 16 H 11 N 3 O 2

formula text :

C16H11N3O2

cas num :

160807-49-8

2020 USD :

183

2021 USD :

189 USD

alt names :

Indirubin-3 -monoxime

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage