WAY 161503 hydrochloride | Tocris Bioscience 1801/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

WAY 161503 hydrochloride

catalog :

1801/10

quantity :

10 mg (also 50 mg)

price :

200 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Hirono M, Nagao S, Yanagawa Y, Konishi S. Monoaminergic modulation of GABAergic transmission onto cerebellar globular cells. Neuropharmacology. 2017;118:79-89 pubmed publisher
Doslikova B, Garfield A, Shaw J, Evans M, Burdakov D, Billups B, et al. 5-HT2C receptor agonist anorectic efficacy potentiated by 5-HT1B receptor agonist coapplication: an effect mediated via increased proportion of pro-opiomelanocortin neurons activated. J Neurosci. 2013;33:9800-4 pubmed publisher
Banas S, Doly S, Boutourlinsky K, Diaz S, Belmer A, Callebert J, et al. Deconstructing antiobesity compound action: requirement of serotonin 5-HT2B receptors for dexfenfluramine anorectic effects. Neuropsychopharmacology. 2011;36:423-33 pubmed publisher
Mbaki Y, Ramage A. Investigation of the role of 5-HT2 receptor subtypes in the control of the bladder and the urethra in the anaesthetized female rat. Br J Pharmacol. 2008;155:343-56 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1801

SKU :

1801/10

product name :

WAY 161503 hydrochloride

description :

Potent and selective 5-HT2C agonist

target :

5-HT2C Receptor Agonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Desiccate at RT

observed molecular weight :

308.59

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

WAY 161503 hydrochloride is a potent and selective 5-HT2C receptor agonist (Ki = 4 nM; EC50 = 12 nM). Shows approximately 2-fold selectivity for 5HT2C over 5HT2A in HEK293 cell lines (EC50 = 7.3 nM and 12 nM, respectively). Antidepressant following systemic administration in vivo .

product keywords :

Potent selective 5-HT2C agonists Serotonin Receptors WAY161503 hydrochloride 5-HT2C Receptors 1801,

extended description :

Potent and selective 5-HT2C agonist

chemical name text :

8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride

formula :

C11H11Cl2N3O.HCl

formula text :

C11H11Cl2N3O.HCl

cas num :

276695-22-8

USD :

198

USD 2025 :

200 USD

product details :

Potent and selective 5-HT2C agonist

more info or order :

Tocris Bioscience product webpage