WKYMVm | Tocris Bioscience 1800/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

WKYMVm

catalog :

1800/1

quantity :

1 mg

price :

205 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Kienle K, Glaser K, Eickhoff S, Mihlan M, Knöpper K, Reátegui E, et al. Neutrophils self-limit swarming to contain bacterial growth in vivo. Science. 2021;372: pubmed publisher
BiedroÅ„ R, KonopiÅ„ski M, Marcinkiewicz J, JÃ³zefowski S. Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. PLoS ONE. 2015;10:e0123293 pubmed publisher
Thompson D, McArthur S, Hislop J, Flower R, Perretti M. Identification of a novel recycling sequence in the C-tail of FPR2/ALX receptor: association with cell protection from apoptosis. J Biol Chem. 2014;289:36166-78 pubmed publisher
Khau T, Langenbach S, Schuliga M, Harris T, Johnstone C, Anderson R, et al. Annexin-1 signals mitogen-stimulated breast tumor cell proliferation by activation of the formyl peptide receptors (FPRs) 1 and 2. FASEB J. 2011;25:483-96 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1800

SKU :

1800/1

product name :

WKYMVm

description :

FPR1, FPR2 and FPR3 receptor agonist

target :

Formyl Peptide Receptor Agonists

unit size :

1 mg

category :

Peptides

purity :

95%

storage :

Store at -20°C

observed molecular weight :

856.11

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

WKYMVm is a selective agonist for the formyl peptide receptors FPR1, FPR2 (EC50 = 75 pM) and FPR3 (EC50 = 3 nM), expressed on immune cells. Induces Ca2+ mobilization and superoxide production in, and chemotaxic migration of, monocytes and neutrophils. Also promotes monocyte survival through a PKC-, PI 3-kinase- and Akt-dependent pathway.

product keywords :

FPR1 FPR2 FPR3 receptor agonists FPRL Formyl like Peptide Receptors Leukocyte chemoattractant peptide Formyl Peptide Receptors 1800,

extended description :

FPR1, FPR2 and FPR3 receptor agonist

formula :

C41H61N9O7S2

formula text :

C41H61N9O7S2

cas num :

187986-17-0

USD :

202

USD 2025 :

205 USD

product details :

FPR1, FPR2 and FPR3 receptor agonist

alt names :

Leukocyte chemoattractant peptide

more info or order :

Tocris Bioscience product webpage