WKYMVM | Tocris Bioscience 1799/1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

WKYMVM

catalog :

1799/1

quantity :

1 mg

price :

149 USD

citations: 5

Reference
Kienle K, Glaser K, Eickhoff S, Mihlan M, Knöpper K, Reátegui E, et al. Neutrophils self-limit swarming to contain bacterial growth in vivo. Science. 2021;372: pubmed publisher
García Prieto J, Villena Gutiérrez R, Gomez M, Bernardo E, Pun García A, Garcia Lunar I, et al. Neutrophil stunning by metoprolol reduces infarct size. Nat Commun. 2017;8:14780 pubmed publisher
Schepetkin I, Kirpotina L, Khlebnikov A, Cheng N, Ye R, Quinn M. Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones. Biochem Pharmacol. 2014;92:627-41 pubmed publisher
Schepetkin I, Kirpotina L, Khlebnikov A, Leopoldo M, Lucente E, Lacivita E, et al. 3-(1H-indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide enantiomers with human formyl-peptide receptor agonist activity: molecular modeling of chiral recognition by FPR2. Biochem Pharmacol. 2013;85:404-16 pubmed publisher
Schepetkin I, Kirpotina L, Khlebnikov A, Jutila M, Quinn M. Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors. Mol Pharmacol. 2011;79:77-90 pubmed publisher

product information

brand :

Tocris

MasterCode :

1799

SKU :

1799/1

product name :

WKYMVM

unit sizes :

1 mg

description :

Selective FPR2 and FPR3 receptor agonist

target :

Formyl Peptide Receptor Agonists

category :

Peptides

observed molecular weight :

856.11

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

WKYMVM is a selective agonist for the formyl peptide receptors FPR2 and FPR3, expressed on immune cells. EC50 values for induction of calcium mobilization in FPR2-HL-60 cells and FPR3-HL-60 cells are 2 and 80 nM respectively.

extended description :

Selective FPR2 and FPR3 receptor agonist

formula :

C 41 H 61 N 9 O 7 S 2

formula text :

C41H61N9O7S2

cas num :

187986-11-4

USD :

149 USD

product details :

Selective FPR2 and FPR3 receptor agonist

alt names :

W-peptide

storage :

Desiccate at -20°C