product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Zacopride hydrochloride
catalog :
1795/10
quantity :
10 mg (also 50 mg)
price :
194 USD
more info or order :
citations: 3
Reference
Wang Q, Zhang H, Xu H, Guo D, Shi H, Li Y, et al. 5-HTR3 and 5-HTR4 located on the mitochondrial membrane and functionally regulated mitochondrial functions. Sci Rep. 2016;6:37336 pubmed publisher
Otvos R, Iyer J, van Elk R, Ulens C, Niessen W, Somsen G, et al. Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. Toxins (Basel). 2015;7:2336-53 pubmed publisher
Ding Z, Ingraham C, Rodd Z, McBride W. The reinforcing effects of ethanol within the nucleus accumbens shell involve activation of local GABA and serotonin receptors. J Psychopharmacol. 2015;29:725-33 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1795
SKU :
1795/10
product name :
Zacopride hydrochloride
description :
Highly potent 5-HT3 antagonist; also 5-HT4 agonist
target :
5-HT3 Receptor Antagonists
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
99%
storage :
Desiccate at RT
observed molecular weight :
346.26
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Zacopride hydrochloride is a highly potent 5-HT3 receptor antagonist (Ki = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). Antiemetic and anxiolytic following systemic administration in vivo .
product keywords :
5-HT4 agonists potent 5-HT3 antagonists Serotonin Receptors 5-Hydroxytryptamine 5-HT3 Receptors 5-HT4 Receptors 1795,
extended description :
Highly potent 5-HT3 antagonist; also 5-HT4 agonist
chemical name text :
( )-4-Amino-N-1-azabicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxybenzamide hydrochloride
formula :
C15H20ClN3O2.HCl
formula text :
C15H20ClN3O2.HCl
cas num :
101303-98-4
USD :
192
USD 2025 :
194 USD
product details :
Highly potent 5-HT3 antagonist; also 5-HT4 agonist
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK