PKC z pseudosubstrate | Tocris Bioscience 1791 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PKC z pseudosubstrate

catalog :

1791

quantity :

1 mg

price :

352 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Mattson A, Begun D, Molstad D, Meyer M, Oursler M, Westendorf J, et al. Deficiency in the phosphatase PHLPP1 suppresses osteoclast-mediated bone resorption and enhances bone formation in mice. J Biol Chem. 2019;294:11772-11784 pubmed publisher
Mu Y, Sundar R, Thakur N, Ekman M, Gudey S, Yakymovych M, et al. TRAF6 ubiquitinates TGF? type I receptor to promote its cleavage and nuclear translocation in cancer. Nat Commun. 2011;2:330 pubmed publisher

product information

brand :

Tocris

master code :

1791

SKU :

1791/1

product name :

PKC z pseudosubstrate

description :

PKC inhibitor peptide (attached to cell-permeable vector)

target :

Protein Kinase C Inhibitors

category :

Peptides

unit size :

1 mg

observed molecular weight :

4673.59

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Inhibitor of protein kinase C (PKC) ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC pseudosubstrate domain linked by a disulphide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37 C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide. Induces mast cell degranulation by a PKC -independent pathway.

catalog number base :

1791

product keywords :

PKC zeta inhibitors inhibits Protein Kinases C pseudosubstrate PKCz ProteinkinaseC Protein kinase C zeta pseudosubstrate Protein Kinase C 1791,

extended description :

PKC inhibitor peptide (attached to cell-permeable vector)

formula :

C 208 H 336 N 74 O 44 S 3

formula text :

C208H336N74O44S3

2020 USD :

338

2021 USD :

352 USD

alt names :

Protein kinase C zeta pseudosubstrate

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage