product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
GRP (human)
catalog :
1789/1
quantity :
1 mg
price :
382 USD
more info or order :
citations: 6
Reference
Sheahan T, Warwick C, Fanien L, Ross S. The Neurokinin-1 Receptor is Expressed with Gastrin-Releasing Peptide Receptor in Spinal Interneurons and Modulates Itch. J Neurosci. 2020;40:8816-8830 pubmed publisher
Blais K, Sethi J, Tabarean I. Gastrin-releasing peptide receptor mediates the excitation of preoptic GABAergic neurons by bombesin. Neurosci Lett. 2016;633:262-267 pubmed publisher
Gey M, Wanner R, Schilling C, Pedro M, Sinske D, Knöll B. Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury. Open Biol. 2016;6: pubmed publisher
Lee H, Ko M. Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates. Sci Rep. 2015;5:11676 pubmed publisher
Solorzano C, Villafuerte D, Meda K, Cevikbas F, Braz J, Sharif Naeini R, et al. Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concerns. J Neurosci. 2015;35:648-57 pubmed publisher
Kim K, Paul P, Qiao J, Lee S, Chung D. Enhanced autophagy blocks angiogenesis via degradation of gastrin-releasing peptide in neuroblastoma cells. Autophagy. 2013;9:1579-90 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1789
SKU :
1789/1
product name :
GRP (human)
description :
Endogenous GRP receptor agonist
target :
Bombesin Receptor Agonists
unit size :
1 mg
category :
Peptides
purity :
95%
species :
Human
storage :
Store at -20°C
observed molecular weight :
2859.4
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
GRP (human) is a mammalian bombesin-like peptide neurotransmitter that is an agonist for the gastrin-releasing peptide receptor (GRPR). GRP has been reported to activate GABAergic interneurons in the amygdala leading to increased GABA release and fear suppression in mice in vivo . Also involved in mitogenesis, and GI tract and appetite regulation.
product keywords :
Endogenous GRP receptor agonists GRP-Preferring Receptors BB2 Gastrin-Releasing Peptide-Preferring Bombesin Gastrin-releasing peptide (human) Bombesin Receptors 1789,
extended description :
Endogenous GRP receptor agonist
formula :
C130H204N38O31S2
formula text :
C130H204N38O31S2
cas num :
93755-85-2
USD :
370
USD 2025 :
382 USD
product details :
Endogenous GRP receptor agonist
alt names :
Gastrin-releasing peptide (human)
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK