product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Dynamin inhibitory peptide
catalog :
1774
quantity :
1 mg
price :
292 USD
more info or order :
citations: 13
Reference
Falgairolle M, O Donovan M. Pharmacological Investigation of Fluoro-Gold Entry into Spinal Neurons. PLoS ONE. 2015;10:e0131430 pubmed publisher
Glebov O, Tigaret C, Mellor J, Henley J. Clathrin-independent trafficking of AMPA receptors. J Neurosci. 2015;35:4830-6 pubmed publisher
Pleil K, Rinker J, Lowery Gionta E, Mazzone C, McCall N, Kendra A, et al. NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking. Nat Neurosci. 2015;18:545-52 pubmed publisher
Yuen E, Qin L, Wei J, Liu W, Liu A, Yan Z. Synergistic regulation of glutamatergic transmission by serotonin and norepinephrine reuptake inhibitors in prefrontal cortical neurons. J Biol Chem. 2014;289:25177-85 pubmed publisher
Chiang H, Shin W, Zhao W, HAMID E, Sheng J, Baydyuk M, et al. Post-fusion structural changes and their roles in exocytosis and endocytosis of dense-core vesicles. Nat Commun. 2014;5:3356 pubmed publisher
Chamma I, Heubl M, Chevy Q, Renner M, Moutkine I, Eugène E, et al. Activity-dependent regulation of the K/Cl transporter KCC2 membrane diffusion, clustering, and function in hippocampal neurons. J Neurosci. 2013;33:15488-503 pubmed publisher
Zhu Y, Dua S, Gold M. Inflammation-induced shift in spinal GABA(A) signaling is associated with a tyrosine kinase-dependent increase in GABA(A) current density in nociceptive afferents. J Neurophysiol. 2012;108:2581-93 pubmed publisher
Cuitino L, Godoy J, Farías G, Couve A, Bonansco C, Fuenzalida M, et al. Wnt-5a modulates recycling of functional GABAA receptors on hippocampal neurons. J Neurosci. 2010;30:8411-20 pubmed publisher
Graziane N, Yuen E, Yan Z. Dopamine D4 Receptors Regulate GABAA Receptor Trafficking via an Actin/Cofilin/Myosin-dependent Mechanism. J Biol Chem. 2009;284:8329-36 pubmed publisher
Dewerchin H, Cornelissen E, Van Hamme E, Smits K, Verhasselt B, Nauwynck H. Surface-expressed viral proteins in feline infectious peritonitis virus-infected monocytes are internalized through a clathrin- and caveolae-independent pathway. J Gen Virol. 2008;89:2731-40 pubmed publisher
Grueter B, McElligott Z, ROBISON A, Mathews G, Winder D. In vivo metabotropic glutamate receptor 5 (mGluR5) antagonism prevents cocaine-induced disruption of postsynaptically maintained mGluR5-dependent long-term depression. J Neurosci. 2008;28:9261-70 pubmed publisher
Xia Y, Nawy S, Carroll R. Activity-dependent synaptic plasticity in retinal ganglion cells. J Neurosci. 2007;27:12221-9 pubmed
Jiang Q, Yan Z, Feng J. Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism. J Neurosci. 2006;26:4318-28 pubmed
product information
brand :
Tocris
master code :
1774
SKU :
1774/1
product name :
Dynamin inhibitory peptide
description :
Dynamin inhibitor
target :
Dynamin Inhibitors
category :
Peptides
unit size :
1 mg
observed molecular weight :
1121.26
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Peptide inhibitor of the GTPase dynamin; competitively blocks binding of dynamin to amphiphysin thus prevents endocytosis when administered intracellularly. Reduces GABAA receptor internalization and increases miniature ISPC amplitude and frequency in neurons expressing GABAA receptors. . Cell-permeable version also available.
catalog number base :
1774
product keywords :
Dynamin inhibitors inhibits Mitosis Epac GTPases P4 Mitosis Dynamin 1774,
extended description :
Dynamin inhibitor
formula :
C 47 H 80 N 18 O 14
formula text :
C47H80N18O14
cas num :
251634-21-6
2020 USD :
286
2021 USD :
292 USD
alt names :
P4
storage :
Desiccate at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK