S 14506 hydrochloride | Tocris Bioscience 1771 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

S 14506 hydrochloride

catalog :

1771

quantity :

10 mg (also 50 mg)

price :

164 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Walory J, Mielczarek L, Jarończyk M, Koronkiewicz M, Kossakowski J, Bugno R, et al. Oncotoxic Properties of Serotonin Transporter Inhibitors and 5-HT1A Receptor Ligands. Int J Mol Sci. 2018;19: pubmed publisher

product information

brand :

Tocris

master code :

1771

SKU :

1771/10

product name :

S 14506 hydrochloride

description :

Highly potent 5-HT1A agonist; displays unique binding mechanism

target :

5-HT1 Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

443.94

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). Possibly binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Anxiolytic following central administration in vivo .

catalog number base :

1771

product keywords :

potent 5-HT1A agonists Serotonin Receptors S14506 hydrochloride 5-HT1A Receptors 1771,

extended description :

Highly potent 5-HT1A agonist; displays unique binding mechanism

chemical name text :

4-Fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]benzamide hydrochloride

formula :

C 24 H 26 FN 3 O 2 .HCl

formula text :

C24H26FN3O2.HCl

cas num :

286369-38-8

2020 USD :

164

2021 USD :

164 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage