ALX 5407 hydrochloride | Tocris Bioscience 1757/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ALX 5407 hydrochloride

catalog :

1757/10

quantity :

10 mg

price :

267 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Yue J, Abraham M, Bauer P, Lapierre M, Wang P, Duca F, et al. Inhibition of glycine transporter-1 in the dorsal vagal complex improves metabolic homeostasis in diabetes and obesity. Nat Commun. 2016;7:13501 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

1757

SKU :

1757/10

product name :

ALX 5407 hydrochloride

description :

Selective non-transportable GlyT1 inhibitor

target :

Glycine Transporter Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Desiccate at +4°C

observed molecular weight :

429.92

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ALX 5407 hydrochloride is a selective non-transportable inhibitor of the glycine transporter GlyT1 (IC50 values are 3 nM and 100 M for human GlyT1c and GlyT2 respectively). Does not recognize other glycine sites, including the glycine site on the NMDA receptor (IC50 100 M). . Racemate also available.

product keywords :

Selective non-transportable GlyT1 inhibitors inhibits Glycine Transporters Monoamine Neurotransmitter ALX5407 hydrochloride (+)-NFPS Glycine Transporters 1757,

extended description :

Selective non-transportable GlyT1 inhibitor

chemical name text :

N-[(3R)-3-([1,1 -Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine hydrochloride

formula :

C24H24FNO3.HCl

formula text :

C24H24FNO3.HCl

cas num :

200006-08-2

USD :

264

USD 2025 :

267 USD

product details :

Selective non-transportable GlyT1 inhibitor

alt names :

(+)-NFPS

more info or order :

Tocris Bioscience product webpage