product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
Isoproterenol hydrochloride
catalog :
1747/100
quantity :
100 mg
price :
147 USD
more info or order :
citations: 29
Reference
Turkieh A, Porouchani S, Beseme O, Chwastyniak M, Amouyel P, Lamblin N, et al. Increased clusterin levels after myocardial infarction is due to a defect in protein degradation systems activity. Cell Death Dis. 2019;10:608 pubmed publisher
Rudnicki M, Abdifarkosh G, Rezvan O, Nwadozi E, Roudier E, Haas T. Female Mice Have Higher Angiogenesis in Perigonadal Adipose Tissue Than Males in Response to High-Fat Diet. Front Physiol. 2018;9:1452 pubmed publisher
Santos R, Frank A, Fátima L, Palmer B, Oz O, Clegg D. Activation of estrogen receptor alpha induces beiging of adipocytes. Mol Metab. 2018;18:51-59 pubmed publisher
Gungor N, Yamamoto R, PARE D. Glutamatergic and gabaergic ventral BNST neurons differ in their physiological properties and responsiveness to noradrenaline. Neuropsychopharmacology. 2018;43:2126-2133 pubmed publisher
McKeithan W, Savchenko A, YU M, Cerignoli F, Bruyneel A, Price J, et al. An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes. Front Physiol. 2017;8:766 pubmed publisher
Komolov K, Du Y, Duc N, Betz R, Rodrigues J, Leib R, et al. Structural and Functional Analysis of a β2-Adrenergic Receptor Complex with GRK5. Cell. 2017;169:407-421.e16 pubmed publisher
Hernández Cascales J. Resveratrol enhances the inotropic effect but inhibits the proarrhythmic effect of sympathomimetic agents in rat myocardium. Peerj. 2017;5:e3113 pubmed publisher
Sun F, Ding X, An S, Tang Y, Yang X, Teng L, et al. Adrenergic DNA damage of embryonic pluripotent cells via β2 receptor signalling. Sci Rep. 2015;5:15950 pubmed publisher
Liu Z, Kennedy O, Cardoso L, Basta Pljakic J, Partridge N, Schaffler M, et al. DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH. FASEB J. 2016;30:635-52 pubmed publisher
Siuda E, McCall J, Al Hasani R, Shin G, Il Park S, Schmidt M, et al. Optodynamic simulation of β-adrenergic receptor signalling. Nat Commun. 2015;6:8480 pubmed publisher
Merino B, Quesada I, Hernández Cascales J. Glucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparison with Isoproterenol. PLoS ONE. 2015;10:e0132884 pubmed publisher
Stoddart L, Johnstone E, Wheal A, Goulding J, Robers M, Machleidt T, et al. Application of BRET to monitor ligand binding to GPCRs. Nat Methods. 2015;12:661-663 pubmed publisher
Lang D, Holzem K, Kang C, Xiao M, Hwang H, Ewald G, et al. Arrhythmogenic remodeling of β2 versus β1 adrenergic signaling in the human failing heart. Circ Arrhythm Electrophysiol. 2015;8:409-19 pubmed publisher
Williams M, Li C, Kash T, Matthews R, Winder D. Excitatory drive onto dopaminergic neurons in the rostral linear nucleus is enhanced by norepinephrine in an α1 adrenergic receptor-dependent manner. Neuropharmacology. 2014;86:116-24 pubmed publisher
Gray E, Guglietta R, Khakh B, O Dell T. Inhibitory interactions between phosphorylation sites in the C terminus of ?-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor GluA1 subunits. J Biol Chem. 2014;289:14600-11 pubmed publisher
Hansen N, Manahan Vaughan D. Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of ?-Adrenergic Receptors. Cereb Cortex. 2015;25:1889-96 pubmed publisher
Zaytseva N, Lynn J, Wu Q, Mudaliar D, Sun H, Kuang P, et al. Resonant waveguide grating biosensor-enabled label-free and fluorescence detection of cell adhesion. Sens Actuators B Chem. 2013;188: pubmed publisher
Yang J, Polanowska Grabowska R, Smith J, Shields C, Saucerman J. PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to ?-adrenergic signaling. J Mol Cell Cardiol. 2014;66:83-93 pubmed publisher
Zhang Z, Cordeiro Matos S, Jego S, Adamantidis A, Séguéla P. Norepinephrine drives persistent activity in prefrontal cortex via synergistic ?1 and ?2 adrenoceptors. PLoS ONE. 2013;8:e66122 pubmed publisher
Silberman Y, Winder D. Corticotropin releasing factor and catecholamines enhance glutamatergic neurotransmission in the lateral subdivision of the central amygdala. Neuropharmacology. 2013;70:316-23 pubmed publisher
Santulli G, Lombardi A, Sorriento D, Anastasio A, Del Giudice C, Formisano P, et al. Age-related impairment in insulin release: the essential role of ?(2)-adrenergic receptor. Diabetes. 2012;61:692-701 pubmed publisher
Rankovic V, Landgraf P, Kanyshkova T, Ehling P, Meuth S, Kreutz M, et al. Modulation of calcium-dependent inactivation of L-type Ca2+ channels via ?-adrenergic signaling in thalamocortical relay neurons. PLoS ONE. 2011;6:e27474 pubmed publisher
Zemkova H, Stojilkovic S, Klein D. Norepinephrine causes a biphasic change in mammalian pinealocye membrane potential: role of alpha1B-adrenoreceptors, phospholipase C, and Ca2+. Endocrinology. 2011;152:3842-51 pubmed publisher
Chigaev A, Smagley Y, Zhang Y, Waller A, Haynes M, Amit O, et al. Real-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4. J Biol Chem. 2011;286:20375-86 pubmed publisher
Nobis W, Kash T, Silberman Y, Winder D. ?-Adrenergic receptors enhance excitatory transmission in the bed nucleus of the stria terminalis through a corticotrophin-releasing factor receptor-dependent and cocaine-regulated mechanism. Biol Psychiatry. 2011;69:1083-90 pubmed publisher
Clark A, Sousa K, Chisolm C, MacDougald O, Kennedy R. Reversibly sealed multilayer microfluidic device for integrated cell perfusion and on-line chemical analysis of cultured adipocyte secretions. Anal Bioanal Chem. 2010;397:2939-47 pubmed publisher
Duncan M, Hester J, Hopper J, Franklin K. The effects of aging and chronic fluoxetine treatment on circadian rhythms and suprachiasmatic nucleus expression of neuropeptide genes and 5-HT1B receptors. Eur J Neurosci. 2010;31:1646-54 pubmed publisher
Maehashi K, Matano M, Wang H, Vo L, Yamamoto Y, Huang L. Bitter peptides activate hTAS2Rs, the human bitter receptors. Biochem Biophys Res Commun. 2008;365:851-5 pubmed
Cardin J, Schmidt M. Noradrenergic inputs mediate state dependence of auditory responses in the avian song system. J Neurosci. 2004;24:7745-53 pubmed
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1747
SKU :
1747/100
product name :
Isoproterenol hydrochloride
description :
Standard selective agonist
target :
Non-selective Adrenergic beta Receptor Agonists
unit size :
100 mg
category :
Small Molecules
purity :
98%
storage :
Store at RT
observed molecular weight :
247.72
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Isoproterenol hydrochloride is a standard selective -adrenoceptor agonist; vasorelaxant and bronchodilator. Activation of 2 receptors activates downstream PKA and ERK, and may stimulate NO-mediated endothelium-dependent smooth muscle relaxation. Active in vivo .
product keywords :
selective -adrenoceptor beta-adrenoceptor b-adrenoceptor -adrenergic beta-adrenergic b-adrenergic agonists Receptors Non-Selective Isoprenaline Non-selective Adrenergic Beta Receptors 1747,
extended description :
Standard selective agonist
chemical name text :
4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol hydrochloride
formula :
C11H17NO3.HCl
formula text :
C11H17NO3.HCl
cas num :
51-30-9
USD :
141
USD 2025 :
147 USD
product details :
Standard selective agonist
alt names :
Isoprenaline
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK