Nemonapride | Tocris Bioscience 1746/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Nemonapride

catalog :

1746/10

quantity :

10 mg (also 50 mg)

price :

238 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Gadgaard C, Jensen A. Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay. Biochem Pharmacol. 2020;175:113870 pubmed publisher

product information

brand :

Tocris

catalog number base :

1746

SKU :

1746/10

product name :

Nemonapride

units size :

10 mg (also 50 mg)

description :

Highly potent D2-like antagonist; also 5-HT1A agonist

target :

Non-selective Dopamine Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

387.91

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Nemonapride is a highly potent dopamine D2-like receptor antagonist; selective over D1-like receptors (Ki values are 0.1 and 740 nM for D2-like and D1-like receptors respectively). Also potent 5-HT1A receptor agonist (IC50 = 34 nM) and has affinity for sigma receptors.

top caption :

Highly potent D2-like antagonist; also 5-HT1A agonist

extended description :

Highly potent D2-like antagonist; also 5-HT1A agonist

chemical name text :

cis-5-Chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide

formula :

C21H26ClN3O2

formula text :

C21H26ClN3O2

cas num :

75272-39-8

USD :

238 USD

product details :

Highly potent D2-like antagonist; also 5-HT1A agonist

alt names :

YM 09151,YM 09151-2

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage