product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Ionomycin calcium salt
catalog :
1704/1
quantity :
1 mg
price :
214 USD
more info or order :
citations: 18
Reference
Deng Y, Xia X, Zhao Y, Zhao Z, Martínez C, Yin W, et al. Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance. Nat Commun. 2021;12:7041 pubmed publisher
Mihara H, Uchida K, Koizumi S, Moriyama Y. Involvement of VNUT-exocytosis in transient receptor potential vanilloid 4-dependent ATP release from gastrointestinal epithelium. PLoS ONE. 2018;13:e0206276 pubmed publisher
Arcuri C, Monarca L, Ragonese F, Mecca C, Bruscoli S, Giovagnoli S, et al. Probing Internalization Effects and Biocompatibility of Ultrasmall Zirconium Metal-Organic Frameworks UiO-66 NP in U251 Glioblastoma Cancer Cells. Nanomaterials (Basel). 2018;8: pubmed publisher
Mikolajewicz N, Zimmermann E, Willie B, Komarova S. Mechanically stimulated ATP release from murine bone cells is regulated by a balance of injury and repair. elife. 2018;7: pubmed publisher
van Nieuwenhuijze A, Burton O, Lemaitre P, Denton A, Cascalho A, Goodchild R, et al. Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations. Front Immunol. 2018;9:2234 pubmed publisher
Su W, Wu F, Jin Z, Gu Y, Chen Y, Fei Y, et al. Overexpression of P2X4 receptor in Schwann cells promotes motor and sensory functional recovery and remyelination via BDNF secretion after nerve injury. Glia. 2019;67:78-90 pubmed publisher
Azab W, Gramatica A, Herrmann A, Osterrieder N. Binding of alphaherpesvirus glycoprotein H to surface α4β1-integrins activates calcium-signaling pathways and induces phosphatidylserine exposure on the plasma membrane. MBio. 2015;6:e01552-15 pubmed publisher
Plog S, Klymiuk N, Binder S, Van Hook M, Thoreson W, Gruber A, et al. Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype. PLoS ONE. 2015;10:e0140050 pubmed publisher
Jonas R, Klusch A, Schmelz M, Petersen M, Carr R. Assessment of TTX-s and TTX-r Action Potential Conduction along Neurites of NGF and GDNF Cultured Porcine DRG Somata. PLoS ONE. 2015;10:e0139107 pubmed publisher
Shambharkar P, Bittinger M, Latario B, Xiong Z, Bandyopadhyay S, Davis V, et al. TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis. PLoS ONE. 2015;10:e0127480 pubmed publisher
Son G, Yang Y, Park W, Chang I, Shin D. Hypotonic stress induces RANKL via transient receptor potential melastatin 3 (TRPM3) and vaniloid 4 (TRPV4) in human PDL cells. J Dent Res. 2015;94:473-81 pubmed publisher
Barcomb K, Coultrap S, Bayer K. Enzymatic activity of CaMKII is not required for its interaction with the glutamate receptor subunit GluN2B. Mol Pharmacol. 2013;84:834-43 pubmed publisher
Soltoff S, Lannon W. Activation of ERK1/2 by store-operated calcium entry in rat parotid acinar cells. PLoS ONE. 2013;8:e72881 pubmed publisher
Rojas A, Wetherington J, Shaw R, Serrano G, Swanger S, Dingledine R. Activation of group I metabotropic glutamate receptors potentiates heteromeric kainate receptors. Mol Pharmacol. 2013;83:106-21 pubmed publisher
Shahidullah M, Mandal A, Delamere N. TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity. Am J Physiol Cell Physiol. 2012;302:C1751-61 pubmed publisher
Selway J, Rigatti R, Storey N, Lu J, Willars G, Herbert T. Evidence that Ca2+ within the microdomain of the L-type voltage gated Ca2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1. PLoS ONE. 2012;7:e33004 pubmed publisher
Makhortova N, Hayhurst M, Cerqueira A, Sinor Anderson A, Zhao W, Heiser P, et al. A screen for regulators of survival of motor neuron protein levels. Nat Chem Biol. 2011;7:544-52 pubmed publisher
Ohya S, Niwa S, Yanagi A, Fukuyo Y, Yamamura H, Imaizumi Y. Involvement of dominant-negative spliced variants of the intermediate conductance Ca2+-activated K+ channel, K(Ca)3.1, in immune function of lymphoid cells. J Biol Chem. 2011;286:16940-52 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1704
SKU :
1704/1
product name :
Ionomycin calcium salt
description :
Calcium ionophore
target :
Calcium Signaling Agents
unit size :
1 mg
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
747.08
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Ionomycin calcium salt is a calcium ionophore; more specific than A23187 . . Free Acid also available.
product keywords :
Calcium ionophore Ca2+ Ionophore Signaling Signalling Agents General antibiotics General Calcium Signaling Agents Ionophores Antibiotics 1704, trans-NED 19, trans-NED19, ned K,
extended description :
Calcium ionophore
chemical name text :
(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2 R,5S,5 S)-octahydro-5 -[(1R)-1-hydroxyethyl]-2,5 -dimethyl[2,2 -bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid calcium salt
formula :
C41H70O9.Ca
formula text :
C41H70O9.Ca
cas num :
56092-82-1
USD :
205
USD 2025 :
214 USD
product details :
Calcium ionophore
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK