product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
N6-Cyclopentyladenosine
catalog :
1702/50
quantity :
50 mg
price :
163 USD
more info or order :
citations: 12
Reference
Ledderose C, Hefti M, Chen Y, Bao Y, Seier T, Li L, et al. Adenosine arrests breast cancer cell motility by A3 receptor stimulation. Purinergic Signal. 2016;12:673-685 pubmed
Kavanagh K, Schreiner D, Levis S, O Neill C, Bachtell R. Role of adenosine receptor subtypes in methamphetamine reward and reinforcement. Neuropharmacology. 2015;89:265-73 pubmed publisher
Pakhomov A, Semenov I, Xiao S, Pakhomova O, Gregory B, Schoenbach K, et al. Cancellation of cellular responses to nanoelectroporation by reversing the stimulus polarity. Cell Mol Life Sci. 2014;71:4431-41 pubmed publisher
Nguyen M, Lee S, Ross A, Ryals M, Choudhry V, Venton B. Characterization of spontaneous, transient adenosine release in the caudate-putamen and prefrontal cortex. PLoS ONE. 2014;9:e87165 pubmed publisher
Kozma E, Gizewski E, Tosh D, Squarcialupi L, Auchampach J, Jacobson K. Characterization by flow cytometry of fluorescent, selective agonist probes of the A(3) adenosine receptor. Biochem Pharmacol. 2013;85:1171-81 pubmed publisher
Lopez Sanjurjo C, Tovey S, Prole D, Taylor C. Lysosomes shape Ins(1,4,5)P3-evoked Ca2+ signals by selectively sequestering Ca2+ released from the endoplasmic reticulum. J Cell Sci. 2013;126:289-300 pubmed publisher
Lemieux M, Labrecque S, Tardif C, Labrie Dion É, Lebel E, De Koninck P. Translocation of CaMKII to dendritic microtubules supports the plasticity of local synapses. J Cell Biol. 2012;198:1055-73 pubmed publisher
Hobson B, Merritt K, Bachtell R. Stimulation of adenosine receptors in the nucleus accumbens reverses the expression of cocaine sensitization and cross-sensitization to dopamine D2 receptors in rats. Neuropharmacology. 2012;63:1172-81 pubmed publisher
Sousa V, Assaife Lopes N, Ribeiro J, Pratt J, Brett R, Sebastião A. Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of ?9-tetrahydrocannabinol on spatial memory. Neuropsychopharmacology. 2011;36:472-87 pubmed publisher
Bender V, Pugh J, Jahr C. Presynaptically expressed long-term potentiation increases multivesicular release at parallel fiber synapses. J Neurosci. 2009;29:10974-8 pubmed publisher
Jensen T, Filoteo A, Knopfel T, Empson R. Presynaptic plasma membrane Ca2+ ATPase isoform 2a regulates excitatory synaptic transmission in rat hippocampal CA3. J Physiol. 2007;579:85-99 pubmed
Villalba N, Stankevicius E, García Sacristán A, Simonsen U, Prieto D. Contribution of both Ca2+ entry and Ca2+ sensitization to the alpha1-adrenergic vasoconstriction of rat penile small arteries. Am J Physiol Heart Circ Physiol. 2007;292:H1157-69 pubmed
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1702
SKU :
1702/50
product name :
N6-Cyclopentyladenosine
description :
Potent and selective A1 agonist
target :
Adenosine A1 Receptor Agonists
unit size :
50 mg
category :
Small Molecules
purity :
99%
storage :
Desiccate at +4°C
observed molecular weight :
335.36
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
N 6-Cyclopentyladenosine is a potent and selective adenosine A1 receptor agonist (Ki values are 2.3, 790 and 43 nM for human A1, A2A and A3 receptors respectively; EC50 = 18600 nM for hA2B). Centrally active following systemic administration in vivo .
product keywords :
Potent selective A1 agonists Receptors adenosines CPA Adenosine A1 Receptors 1702,
extended description :
Potent and selective A1 agonist
chemical name text :
N-Cyclopentyladenosine
formula :
C15H21N5O4
formula text :
C15H21N5O4
cas num :
41552-82-3
USD :
161
USD 2025 :
163 USD
product details :
Potent and selective A1 agonist
alt names :
CPA
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK