product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
CGS 15943
catalog :
1699
quantity :
10 mg (also 50 mg)
price :
85 USD
more info or order :
citations: 6
Reference
Wakisaka N, Miyasaka N, Koide T, Masuda M, Hiraki Kajiyama T, Yoshihara Y. An Adenosine Receptor for Olfaction in Fish. Curr Biol. 2017;27:1437-1447.e4 pubmed publisher
Avanzato D, Genova T, Fiorio Pla A, Bernardini M, Bianco S, Bussolati B, et al. Activation of P2X7 and P2Y11 purinergic receptors inhibits migration and normalizes tumor-derived endothelial cells via cAMP signaling. Sci Rep. 2016;6:32602 pubmed publisher
Stoddart L, Johnstone E, Wheal A, Goulding J, Robers M, Machleidt T, et al. Application of BRET to monitor ligand binding to GPCRs. Nat Methods. 2015;12:661-663 pubmed publisher
Diógenes M, Neves Tomé R, Fucile S, Martinello K, Scianni M, Theofilas P, et al. Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase. Cereb Cortex. 2014;24:67-80 pubmed publisher
Sivaramakrishnan V, Bidula S, Campwala H, Katikaneni D, Fountain S. Constitutive lysosome exocytosis releases ATP and engages P2Y receptors in human monocytes. J Cell Sci. 2012;125:4567-75 pubmed publisher
Ilie A, Raimondo J, Akerman C. Adenosine release during seizures attenuates GABAA receptor-mediated depolarization. J Neurosci. 2012;32:5321-32 pubmed publisher
product information
brand :
Tocris
master code :
1699
SKU :
1699/10
product name :
CGS 15943
description :
Potent adenosine receptor antagonist
target :
Non-selective Adenosine Receptor Antagonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
285.69
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent adenosine receptor antagonist (Ki values are 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors respectively). Orally active in vivo .
catalog number base :
1699
product keywords :
Potent adenosines receptor antagonists Non-Selective Receptors CGS15943 Non-selective Adenosine 1699,
extended description :
Potent adenosine receptor antagonist
chemical name text :
9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
formula :
C 13 H 8 ClN 5 O
formula text :
C13H8ClN5O
cas num :
104615-18-1
2020 USD :
82
2021 USD :
85 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK