Noscapine hydrochloride | Tocris Bioscience 1697/100 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Noscapine hydrochloride

catalog :

1697/100

quantity :

100 mg

price :

99 USD

citations: 1

Reference
Rennekamp A, Huang X, Wang Y, Patel S, Lorello P, Cade L, et al. ?1 receptor ligands control a switch between passive and active threat responses. Nat Chem Biol. 2016;12:552-8 pubmed publisher

product information

brand :

Tocris

MasterCode :

1697

SKU :

1697/100

product name :

Noscapine hydrochloride

unit sizes :

100 mg

description :

Tubulin inhibitor; induces apoptosis

target :

Microtubule Binding Compounds

category :

Small Molecules

purity :

99%

observed molecular weight :

449.88

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Noscapine hydrochloride is an opioid alkaloid with several actions. Binds to tubulin, arrests cells in mitosis and induces apoptosis. Antagonist at bradykinin receptors (pA2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated cAMP increases in CNS tissues. Modulates IKK activation, suppressing the NF- B signaling pathway. Blocks proliferation of human leukemia and multiple myeloma cells. Exhibits anti-inflammatory activity.

extended description :

Tubulin inhibitor; induces apoptosis

chemical name text :

(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone hydrochloride

formula :

C 22 H 23 NO 7 .HCl

formula text :

C22H23NO7.HCl

cas num :

912-60-7

USD :

99 USD

product details :

Tubulin inhibitor; induces apoptosis

storage :

Desiccate at RT