product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Cisapride
catalog :
1695/10
quantity :
10 mg (also 50 mg)
price :
184 USD
more info or order :
citations: 4
Reference
Padayatti P, Wang L, Gupta S, Orban T, Sun W, Salom D, et al. A hybrid structural approach to analyze ligand binding by the serotonin type 4 receptor (5-HT4). Mol Cell Proteomics. 2013;12:1259-71 pubmed publisher
Beattie D, Armstrong S, Vickery R, Tsuruda P, Campbell C, Richardson C, et al. The Pharmacology of TD-8954, a Potent and Selective 5-HT(4) Receptor Agonist with Gastrointestinal Prokinetic Properties. Front Pharmacol. 2011;2:25 pubmed publisher
Murray K, Stephens M, Rank M, D Amico J, Gorassini M, Bennett D. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. J Neurophysiol. 2011;106:925-43 pubmed publisher
Xiang Z, Wang L, Kitai S. Modulation of spontaneous firing in rat subthalamic neurons by 5-HT receptor subtypes. J Neurophysiol. 2005;93:1145-57 pubmed
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
1695
SKU :
1695/10
product name :
Cisapride
description :
5-HT4 agonist; stimulates intestinal ACh release
target :
5-HT4 Receptor Agonists
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
99%
storage :
Store at RT
observed molecular weight :
465.95
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Cisapride is a 5-HT4 receptor agonist and gastrokinetic agent. Stimulates intestinal acetylcholine release, possibly via 5-HT4 receptor-dependent and -independent mechanisms, leading to increased intestinal motility.
product keywords :
5-HT4 agonists stimulates Serotonin Receptors 5-Hydroxytryptamine stimulate ACh acetylcholine release nicotinic muscarinic nAChR R51619 R 51619 Other Acetylcholine 5-HT4 Receptors Non-selective Muscarinics 1695,
extended description :
5-HT4 agonist; stimulates intestinal ACh release
chemical name text :
( )-4-Amino-5-chloro-N-[1-[(3R*,4S*)-3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide
formula :
C23H29ClFN3O4
formula text :
C23H29ClFN3O4
cas num :
81098-60-4
USD :
176
USD 2025 :
184 USD
product details :
5-HT4 agonist; stimulates intestinal ACh release
alt names :
R 51619
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK