K 252a | Tocris Bioscience 1683/200 product information

product summary

request information :

company name :

Tocris Bioscience

product type :

chemical

product name :

K 252a

catalog :

1683/200

quantity :

200µg

price :

245 USD

more info or order :

Tocris Bioscience product webpage

product information

CHEMISTRY :

[H][C@](C[C@]8(O)[C@@](OC)=O)(O[C@]78C)N5C3=C2N7C1=CC=CC=C1C2=C(CNC6=O)C6=C3C4=CC=CC=C45

Cat Number :

1683/200

Product Name :

K 252a

Cas Number :

[99533-80-9]

Unit Size :

200µg

Size :

200

Unit :

µg

USD :

245 USD

Primary Category :

Enzymes

Secondary Category :

Kinases

Tertiary Category :

Broad Spectrum Protein Kinase Inhibitors

Primary Action :

Protein kinase inhibitor

Biological Description :

Non-selective protein kinase inhibitor; analog of staurosporine (Cat.No. 1285). Inhibits PKC (IC50 = 32.9 nM), Ca2+/calmodulin-stimulated phosphodiesterases (IC50 = 1.3 - 2.9 μM), MLCK (Ki = 20 nM) and receptor tyrosine kinases. Inhibits the oncogenic properties of MET; prevents autophosphorylation and activation of downstream effectors (MAPK, Akt).

Formula :

C27H21N3O5

Molwt :

467.48

Synonyms :

SF 2370

more info or order :

Tocris Bioscience product webpage