T 0156 hydrochloride | Tocris Bioscience 1676 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

T 0156 hydrochloride

catalog :

1676

quantity :

10 mg (also 50 mg)

price :

140 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Sikka G, Hussmann G, Pandey D, Cao S, Hori D, Park J, et al. Melanopsin mediates light-dependent relaxation in blood vessels. Proc Natl Acad Sci U S A. 2014;111:17977-82 pubmed publisher

product information

brand :

Tocris

master code :

1676

SKU :

1676/10

product name :

T 0156 hydrochloride

description :

Highly potent, selective PDE5 inhibitor

target :

Phosphodiesterase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

620.06

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective inhibitor of phosphodiesterase type 5 (PDE5); more selective than sildenafil (IC50 values are 0.23, 56 and 63000 nM for T 0156 and 3.6, 29 and 270 nM for sildenafil at PDE5, PDE6 and PDEs 1 - 4 respectively). Selective over 30 other enzymes and receptors (IC50 10 mM) and potentiates electrical field stimulation-induced relaxation of isolated rabbit corpus cavernosum. Active in vivo .

catalog number base :

1676

product keywords :

potent selective PDE5 inhibitors inhibits Phosphodiesterases T0156 hydrochloride Phosphodiesterases 1676,

extended description :

Highly potent, selective PDE5 inhibitor

chemical name text :

1,2-Dihydro-2-[(2-methyl-4-pyridinyl)methyl]-1-oxo-8-(2-pyrimidinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-2,7-naphthyridine-3-carboxylic acid methyl ester hydrochloride

formula :

C 31 H 29 N 5 O 7 .HCl

formula text :

C31H29N5O7.HCl

cas num :

324572-93-2

2020 USD :

140

2021 USD :

140 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage